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YpeB

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Bacillus subtilis YpeB holds SleB inactive preventing cortex peptidoglycan degradation during spore dormancy

Bacterial endospores are encased in a thick layer of specialized peptidoglycan called the cortex that is essential for core dehydration and heat resistance. Spore germination and outgrowth requires cortex degradation by enzymes that are deposited in the spore during sporulation. How these enzymes are held inactive during dormancy and activated during germination remains poorly understood.

bioRxiv 8d ago