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Related Articles from SNS
Structural Connectivity Between the Zinc Linchpin Motif, the cluster, and the active site orchestrates DNA repair in MUTYH
The DNA glycosylase MUTYH protects genomic integrity by excising adenine mispaired with 8-oxoguanine (OG), which initiates base excision repair (BER). The [4Fe-4S] cluster DNA binding domain and Zn linchpin motif of MUTYH are hotspots for inherited cancer associated variants (CAVs) highlighting their critical functions in DNA repair. Here, we present three full-length human MUTYH crystal structures bound to DNA across three catalytic states, representing early and late transition states and...
A Reduced-Order Particle-in-Cell Method with Azimuthal Fourier-Decomposed Fields for Nominally Axisymmetric Plasmas
Announce Type: replace Abstract: A reduced-order Particle-in-Cell method is introduced for kinetic simulation of otherwise axisymmetric cylindrical plasmas that exhibit azimuthal instabilities. The method spatially decomposes all field quantities into a small number of (mesh-less) azimuthal Fourier modes $m=0,...,N_m,\quad N_m \ll N_\theta$, reducing the costly three-dimensional field solve $\mathcal{O}(N_zN_rN_\theta)$ to a family of decoupled independent two-dimensional problems...
Bragg-enhanced time-domain Brillouin scattering from a propagating acoustic grating
Announce Type: new Abstract: Generation and detection of coherent phonons in semiconductors by femtosecond optical pulses is a powerful tool for high-frequency acoustic control of their electronic properties. Here, we demonstrate a propagating one-dimensional acoustic grating in bulk semiconductors using above-band-gap excitation by a train of laser pulses with high repetition rate of 1 GHz. This approach enables shaping of the coherent acoustic phonon spectrum and leads to a significant...
Control of Electrons Spin Eliminates Hydrogen Peroxide Formation During Water Splitting
arXiv:2606.01648v1 Announce Type: new Abstract: The production of hydrogen through water splitting in a photoelectrochemical cell suffers from an overpotential that limits the efficiencies. In addition, hydrogen-peroxide formation is identified as a competing process affecting the oxidative stability of photoelectrodes.
ATML1-GIR1-TPL/TPR transcriptional repression module controls glucosinolates and giant cells in Arabidopsis thaliana sepals
Glucosinolates (GSLs) are sulfur- and nitrogen-containing secondary metabolites that serve as defense compounds in Arabidopsis and other members of the Brassicales. Although the enzymatic pathway that produces GSLs is well-studied, the upstream mechanisms that control their tissue-specific synthesis are poorly understood. We identified a novel repression module that transcriptionally regulates GSL levels in sepals, the modified leaves that protect reproductive tissues within the floral bud.
Absolute intensity measurement of pulsed muon beams using in-beam activation
Announce Type: new Abstract: The absolute number of negative muons contained in a beam is essential for many experiments at accelerator facilities, but determining it in pulsed beams has been difficult, particularly at high intensities. The method utilizing the yield of the $\beta$ delayed $\gamma$ rays from the residual nuclei after the muon nuclear capture reaction has recently been developed to determine the muon number in the pulsed muon beam. In particular, the in-beam activation method...