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'Lifting the shame that was never mine to carry' - alleged victim of Al Fayed associate

Joanna Brittan has been identified as a potential modern slavery victim following allegations of rape and trafficking. The claims involve an associate of Al Fayed.

BBC News 13d ago

Integrative genomics reveals shared and stress-specific adaptive pathways underlying acidic soil-associated metal toxicity in rice

Soil acidity-associated toxicities of aluminum (Al), cadmium (Cd), and manganese (Mn) severely constrain rice productivity in upland ecosystems. To investigate the genomic basis of adaptation to acidic soil-related metal stress, we conducted an integrated meta-QTL (M-QTL) and functional genomics analysis in rice. Meta-analysis of 681 QTLs and MTAs from 53 QTL mapping and GWAS studies identified 79 robust M-QTLs, including ten overlapping regions associated with Al-, Cd-, and Mn-responsive...

bioRxiv 7d ago

Police 'sent details of alleged Mohammed Al Fayed trafficking survivor to wrong person' in 'appalling error'

Police 'sent details of alleged Mohammed Al Fayed trafficking survivor to wrong person' in 'appalling error' An alleged victim of ex-Harrods boss Mohammed Al Fayed and his business associate said her police statement was sent by the force to another person A woman who claimed she was a victim of Mohammed Al Fayed said the police sent her details to the wrong person. Joanna Brittan, from Devon, alleged she was trafficked by the former Harrods owners and raped by his business associate. The...

Daily Mirror 7d ago

Building user-driven climate adaptation products

Abstract Climate adaptation products have traditionally been developed using a supply-driven model reliant on available climate information, leading to usability gaps1,2,3,4. To better meet user needs, the climate services field has recognized a need to shift towards a demand-driven model emphasizing co-production, that is, user-driven, scientifically informed products created through shared knowledge practices1,2,3,4,5. However, co-production can be challenging, especially for researchers...

Nature 17h ago

Mutation-dependent responses to sleep and exercise in clonal haematopoiesis

Abstract Clonal haematopoiesis (CH) activates inflammation and increases the risk of atherosclerosis1,2. Whether lifestyle alters CH clone expansion or the phenotypic programming of CH mutant cells, thereby affecting atherosclerosis, is unknown. Here, in humans and mice and across mutations in Jak2, Tet2, Trp53 and Dnmt3a, we demonstrate mutation-dependent responses to sleep and exercise in CH and show that mutant cells are uniquely sensitive to lifestyle.

Nature 17h ago

A prognostic human brain network for diffuse midline glioma

Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.

Nature 17h ago

SIRT7 regulates dosage compensation and safeguards the female X chromosome

Abstract Sirtuins are deacetylases implicated in stress responses and longevity in mammals1,2. Although their differential impact on disease for the two sexes has been noted3,4,5,6,7, the underlying reasons are unclear. Here, using Sirt7 as a model in mice, we examine the mechanisms leading to sex differences and find that Sirt7−/− female mice have decreased fitness throughout their lifespan.

Nature 17h ago

Associate of synagogue attacker admits terrror charge

Mohammad Bashir drove Jihad Al-Shamie to a military base in Oxfordshire in the months before the attack.

BBC England 5d ago

Gene ancestries reveal diverse microbial associations during eukaryogenesis

Abstract The origin of eukaryotes remains a central enigma in biology1. Continuing debates agree on the pivotal role of a symbiosis between an alphaproteobacterium and an Asgard archaeon2,3. However, the nature, timing and contributions of other potential bacterial partners4,5,6 and the role of interactions with viruses7,8,9 remain contentious.

Nature 17h ago

COVID-era assistance policies may have reduced food insecurity, housing instability

COVID-era assistance policies may have reduced food insecurity, housing instability Lisa Lock Scientific Editor Andrew Zinin Lead Editor In 2018, Caitlin Caspi started a five-year research project looking at how raising the minimum wage could impact nutrition-related health outcomes. Caspi is an associate professor of allied health sciences in the College of Agriculture, Health and Natural Resources (CAHNR), associate director of InCHIP, and the director of food security initiatives for the...

Phys.org 8d ago