dCas
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dCas allele sequestration (das-CRISPR): A Versatile New Method to Achieve Monoallelic Gene Editing in Mouse Embryos and in cell culture.
CRISPR-Cas9 technology is a powerful tool extensively used for genome editing in mouse and many other species. Streptococcus pyogenes Cas9 efficiently cuts both alleles in mouse zygotes leaving many edited embryos without a functional protein that might be needed to sustain development, to survive postnatally or to reproduce, thus complicating its overwhelmingly advantageous use in making gene modifications. About 25% of mouse genes are essential for embryonic development and another 7% are...
Geely says its driver assistance system authorized for use in EU
Geely says its driver assistance system authorized for use in EU June 9 : A driver assistance system developed by Geely has been certified to operate in the European Union, the first time a Chinese auxiliary driving system meets those standards, the automaker said in a statement. Geely is one of many Chinese automakers moving to set up production in Europe to avoid tariffs and increasingly strict regulations on importing foreign-made cars. Geely said its G-ASD (Geely Afari Smart Driving)...