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KromHC: Manifold-Constrained Hyper-Connections with Kronecker-Product Residual Matrices

Announce Type: replace Abstract: The success of Hyper-Connections (HC) in neural networks (NN) has also highlighted issues related to training instability and restricted scalability. The Manifold-Constrained Hyper-Connections (mHC) mitigate these challenges by projecting the residual connection space onto a Birkhoff polytope, however, it faces two issues: 1) its iterative Sinkhorn-Knopp (SK) algorithm does not always yield exactly doubly stochastic residual matrices; 2) mHC incurs a...

arXiv CS 8d ago

Cancer’s favorite escape trick may actually make it easier to kill

Cancer’s favorite escape trick may actually make it easier to kill - Date: - June 4, 2026 - Source: - Baylor College of Medicine - Summary: - Scientists have uncovered a surprising new way the immune system fights cancer, overturning a core belief that has guided immunology for decades. The research found that when cancer cells shut down a key immune-recognition molecule called MHC I—a common trick used to hide from “killer” T cells—they can actually become more vulnerable to attack by a...

Science Daily 6d ago

Beyond Single Solution: Multi-Hypothesis Collaborative Deep Unfolding Network for Image Compressive Sensing

arXiv:2606.03666v1 Announce Type: new Abstract: Recent deep unfolding networks (DUNs) have advanced Compressive Sensing (CS) by effectively integrating iterative optimization with deep learning architectures. However, most CS approaches predominantly confine their inference to a single solution space, neglecting the inherent ill-posedness of CS problems that intrinsically permits multiple plausible candidate hypotheses. In this paper, a novel Multi-Hypothesis Collaborative Deep Unfolding CS...

arXiv CS 7d ago

CaliPPer: quantifying, predicting and improving AI model performance for binding prediction

arXiv:2606.07258v1 Announce Type: new Abstract: Binding prediction models accelerate therapeutic antibody and TCR discovery, but their performance on new datasets is unpredictable, often leading to low discovery rates. Density-ratio methods (PAPE, M-CBPE) provide label-free performance estimation for binary classification, but their assumptions and aggregate-only outputs limit binding prediction on neoepitopes, antigen variants and chemical scaffolds. Here we present CaliPPer (Calibration...

arXiv CS 2d ago

DeRes: Decoupling Residual Stability and Adaptivity for Scalable CTR Prediction

arXiv:2606.07980v1 Announce Type: new Abstract: Transformer-based CTR models face a growing bottleneck at the residual connection: under Pre-Norm, early user-interest signals are diluted layer by layer; the identity skip cannot forget stale interests; and each layer sees only its immediate predecessor, losing long-range cross-layer dependencies. Recent attention-based residual variants (AttnRes) address parts of this in language models, but drop the protective identity skip and have not been...

arXiv CS 1d ago