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Over Rs 57L compensation for man left bedridden after accidents: Why Madras HC stepped in
The Madras high court has nearly doubled the motor accident compensation for a man left completely bedridden and unresponsive after two road accidents, while sharply criticising his advocate for failing to seek enhanced compensation on his behalf. A bench comprising Justice N. Anand Venkatesh and Justice K.K. Ramakrishnan enhanced the compensation from Rs 33,02,600 to Rs 57,98,000, invoking its suo motu powers under Order XLI Rule 33 of the Code of Civil Procedure, after finding that the...
The Hidden Bias of Process Reward Models:PRISM for Rewarding the Right Reasoning
arXiv:2606.09078v1 Announce Type: new Abstract: Process Reward Models (PRMs) improve credit assignment for reasoning by providing step-level feedback. However, we identify a hidden bias in PRMs caused by severe imbalance in step-level training data.
A Theory-Guided LLM Pedagogical Agent for STEM+C Scaffolding Without Over-Reliance
Announce Type: new Abstract: LLM pedagogical agents are proliferating, yet recent findings have raised questions about their adherence to established theories of learning and, by extension, their educational value. Concerns regarding cognitive offloading, over-reliance, and "gaming" behaviors persist and remain largely unaddressed. In response, we developed Copa, an agentic, multi-agent, multimodal Collaborative Peer Agent for STEM+C learning.
A prognostic human brain network for diffuse midline glioma
Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.
Gene ancestries reveal diverse microbial associations during eukaryogenesis
Abstract The origin of eukaryotes remains a central enigma in biology1. Continuing debates agree on the pivotal role of a symbiosis between an alphaproteobacterium and an Asgard archaeon2,3. However, the nature, timing and contributions of other potential bacterial partners4,5,6 and the role of interactions with viruses7,8,9 remain contentious.
The Cross-Architecture Substrate: A Domain-Transcendent, Calibration-Surviving Geometric Invariant of Modern Vision Encoders
arXiv:2606.07882v1 Announce Type: new Abstract: Different vision neural networks -- trained to classify, contrast, reconstruct, or match images to text -- should have correspondingly different internal representations. We report that they do not.
Building user-driven climate adaptation products
Abstract Climate adaptation products have traditionally been developed using a supply-driven model reliant on available climate information, leading to usability gaps1,2,3,4. To better meet user needs, the climate services field has recognized a need to shift towards a demand-driven model emphasizing co-production, that is, user-driven, scientifically informed products created through shared knowledge practices1,2,3,4,5. However, co-production can be challenging, especially for researchers...
The Frame Problem
The Frame Problem To most AI researchers, the frame problem is the challenge of representing the effects of action in logic without having to represent explicitly a large number of intuitively obvious non-effects. But to many philosophers, the AI researchers' frame problem is suggestive of wider epistemological issues. Is it possible, in principle, to limit the scope of the reasoning required to derive the consequences of an action?
SIRT7 regulates dosage compensation and safeguards the female X chromosome
Abstract Sirtuins are deacetylases implicated in stress responses and longevity in mammals1,2. Although their differential impact on disease for the two sexes has been noted3,4,5,6,7, the underlying reasons are unclear. Here, using Sirt7 as a model in mice, we examine the mechanisms leading to sex differences and find that Sirt7−/− female mice have decreased fitness throughout their lifespan.
Mutation-dependent responses to sleep and exercise in clonal haematopoiesis
Abstract Clonal haematopoiesis (CH) activates inflammation and increases the risk of atherosclerosis1,2. Whether lifestyle alters CH clone expansion or the phenotypic programming of CH mutant cells, thereby affecting atherosclerosis, is unknown. Here, in humans and mice and across mutations in Jak2, Tet2, Trp53 and Dnmt3a, we demonstrate mutation-dependent responses to sleep and exercise in CH and show that mutant cells are uniquely sensitive to lifestyle.