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Whole-genome duplication shaped cell-type evolution in the vertebrate brain

Abstract The complex brains of vertebrates have more cell types than those of their closest relatives. Whole-genome duplications (WGDs) occurred during early vertebrate evolution1, but it is unclear whether the duplicated genes (ohnologues) facilitated cell-type evolution. Here using brain single-cell transcriptomes from five chordates—human2, mouse3, lizard4, lamprey5 and amphioxus—we report that many cell-type families with conserved core transcription factors in vertebrates do not show...

Nature 18h ago

Uncertainty Principles for the Number Theoretic Transform

arXiv:2606.08662v1 Announce Type: cross Abstract: Motivated by polynomial identity testing with exponentials (Li and Wu, ITCS'26), we study uncertainty principles for the number-theoretic transform (NTT). We show that the NTT satisfies strong sparsity tradeoffs: For every fixed prime $q$ and for all but finitely many primes $p \equiv 1 \pmod q$ every nonzero $f\in \mathbb F_p^{\mathbb

arXiv CS 1d ago