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A cross-domain tropical species dataset with Chinese vernacular names and CITES source links
Announce Type: new Abstract: We describe a versioned cross-domain dataset of 410,499 active tropical species (working snapshot 2026-04-20) spanning three applied subdomains -- tropical_plants, tropical_aquatic, and tropical_pets -- that share a commercial and regulatory life cycle but are distributed across kingdom-organised biodiversity infrastructures. The resource joins taxonomic identifiers from GBIF, Plants of the World Online, iNaturalist, NCBI Taxonomy, the Catalogue of Life and the...
A 5.3-million-year-old deep-sea whale necropolis in the Diamantina Zone
Abstract Whale falls are biodiversity oases at seabeds1,2,3,4,5,6, yet their record from the oceans has remained sparse and fragmentary6,7. Here we report the discovery of a vast whale necropolis in the Diamantina Zone (4,616- to 7,001-m depth), extending about 1,200 km along the sea floor of the southeastern Indian Ocean. This area has a deep and extensive accumulation comprising five modern natural whale-fall communities and 476 fossil cetaceans recorded.
The Frame Problem
The Frame Problem To most AI researchers, the frame problem is the challenge of representing the effects of action in logic without having to represent explicitly a large number of intuitively obvious non-effects. But to many philosophers, the AI researchers' frame problem is suggestive of wider epistemological issues. Is it possible, in principle, to limit the scope of the reasoning required to derive the consequences of an action?
Transnational history explores the Japanese migration to Canada 1877–1988
Transnational history explores the Japanese migration to Canada 1877–1988 Sadie Harley Scientific Editor Andrew Zinin Lead Editor "Japanese Migration to Canada, 1877–1988," a new reference essay by Masumi Izumi, was published in the Oxford Research Encyclopedia of Migration Studies. The article offers a sweeping, deeply researched account of Japanese migration to Canada from the arrival of the first documented migrant in 1877 through the Canadian government's formal redress settlement of...
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.
A prognostic human brain network for diffuse midline glioma
Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.
Lignin to adipic acid in a high-yield chemical and biological redox process
Abstract Viable manufacturing pathways to produce bio-based chemicals from renewable feedstocks, such as lignin derived from plant biomass, are needed to decarbonize the chemicals manufacturing sector. Converting the recalcitrant lignin polymer to valuable bioproducts remains a longstanding challenge in biorefining, with the highest reported single-product yield from lignin currently around 20 wt% (refs. Most existing lignin depolymerization strategies target aryl–ether bond cleavage, which...
Filipino lawyers move to raise legacy of Pablo Manlapit, forgotten leader of Hawaii labor movement
Filipino lawyers move to raise legacy of Pablo Manlapit, forgotten leader of Hawaii labor movement Recent allegations against César Chavez have sparked a renewed focus on Filipino contributions to the U.S. farmworker movement - Bookmark Decades before Filipino American agricultural workers organized a historic strike in California, Pablo Manlapit was organizing Filipino laborers in Hawaii. Manlapit, who migrated to Honolulu in 1910 to work on sugar plantations, saw the exploitation of other...
The AI IPO Race Heats Up, DOGE Whistleblower Sues Elon Musk, and Instagram Gets Hacked
This week on Uncanny Valley, we discuss why the race among the top AI companies to go public has just gotten started but is already creating bizarre repercussions—including numerous San Francisco real estate listings preferring Anthropic stock instead of cash. They also get into why Donald Trump’s new executive order on AI safety is underwhelming and how hackers were able to use Instagram’s AI chatbot to access high-profile accounts like President Barack Obama’s. Plus, we report on how a...