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A prognostic human brain network for diffuse midline glioma
Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.
EMB 00.01 FRI Andrew Mountbatten-Windsor sublet Royal Lodge cottages to boost private income – despite paying peppercorn rent
EMB 00.01 FRI Andrew Mountbatten-Windsor sublet Royal Lodge cottages to boost private income – despite paying peppercorn rent The former prince gained income from privately subletting three cottages within Royal Lodge, a new report from the National Audit Office shows - Bookmark - CommentsGo to comments Andrew Mountbatten-Windsor sublet three properties on the Royal Lodge estate to boost his private income for more than 20 years – despite paying a “peppercorn rent” himself, a new audit...
Dawn French's quiet village life after leaving 'trendy' town
Dawn French's quiet village life after leaving 'trendy' town The beloved British actress and comedian Dawn French has been an unofficial ambassador for Cornwall for nearly two decades. Dawn French, the beloved actress and comedian celebrated for her roles in 'The Vicar of Dibley' and 'French and Saunders', has become something of an unofficial ambassador for Cornwall. Having made the region her home nearly two decades ago, the TV star, 66, frequently shares glimpses of her coastal lifestyle,...
Rocket launches and reentries harm Earth's ozone layer
Rocket launches and reentries harm Earth's ozone layer Gaby Clark Scientific Editor Andrew Zinin Lead Editor The space industry is surging. In coming years, nearly 10,000 spacecraft are slated to launch into low-Earth orbit for a variety of purposes, such as global surveillance, space tourism, and satellite "megaconstellations" providing internet service. Rocket engine exhaust, as well as the burnup of inactive satellites and rocket parts reentering Earth's atmosphere, releases a suite of...
'Backrooms' Stuns with $81M Debut
This weekend was one for the box office history books. Movie theaters across the nation were jamming with Gen Z crowds, who showed up en masse for not one but two buzzy horror films. A24’s “Backrooms” collected a jaw-dropping, record-breaking $81 million from 3,442 North American theaters in its opening weekend.
Maroons hit with double injury blow ahead of Origin II
Queensland and Brisbane Broncos duo Pat Carrigan and Gehamat Shibasaki have both been ruled out of State of Origin II because of injury. Carrigan left the Broncos dressing rooms in a moon boot after their 30–26 loss to St George Illawarra at Lang Park on Sunday. Scans revealed a syndesmosis injury, which is expected to rule Carrigan out of action for three to four weeks.
Artificial Intelligence for Mathematical Reasoning: An Integrated Survey of Language Models, Neuro-symbolic Systems, and Verified Discovery
arXiv:2606.08728v1 Announce Type: new Abstract: Mathematical reasoning has long served as a stringent test of machine intelligence; over the past decade, it has moved from a niche problem within NLP to one of the most consequential AI frontiers. This survey provides a unified account of the field's evolution, from early rule-based math word problem (MWP) solvers and template-driven geometry systems, through neural expression generation and LLM prompting, to contemporary reasoning models,...
Ahoy, DECmate II the little PDP-8 that could
Now, that's a lot of word processing. But under the hood it's still at least PDP-8 adjacent, even considering its oddities and incompatibilities, and you can make it do many of the things a full-size Eight can. We'll take this basic unit, convert the floppy drives to solid state, tap the video output, and put it through its paces.
A thalamus–brainstem attractor network drives history-biased decisions
Abstract Natural environments often change gradually, making it adaptive to bias decisions on the basis of the recent past — a phenomenon known as serial dependence1,2,3. Large-scale recordings during behaviour have identified that serial dependence is a common motif for decision-making, with neural representations of past experiences found throughout the brain4,5,6,7,8,9,10,11. However, it remains unclear whether this bias arises from dedicated neural circuits with history-specific...
Big 12 preview: Despite the drama, Texas Tech stil...
Back when the NIL era was in its nascent stages, with a new Big 12 and a 12-team College Football Playoff on the way, I wondered if there was room for the emergence of a Clemson-style dynasty from a conference known primarily for the endless number of close games. If some team could craft a recruiting boost from both solid spending and sustained success, perhaps they could ride that to a series of conference titles and, perhaps, even playoff runs? I admittedly didn't have a specific team in...