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Related Articles from SNS

A prognostic human brain network for diffuse midline glioma

Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.

Nature 17h ago

Efficient ageing: Simulated lesion of the structural connectome reveals optimised decline in the healthy ageing brain

Healthy ageing is associated with widespread white-matter change and altered connectome organisation, yet the link between local microstructural decline and whole-brain network communication remains unclear. Here we combined tract-based spatial statistics (TBSS) with probabilistic tractography and graph analysis to quantify the connectome-level consequences of age-sensitive white-matter hotspots. In two independent diffusion MRI datasets of healthy young and older adults (n = 144 total;...

bioRxiv 8d ago

Scientists reveal surprising brain benefit of laughter: 'It's a mental workout'

The old saying that laughter is the best medicine may be true, according to new research that suggests it is also a vital catalyst for children's development. Laughter and play are fundamental to healthy brain growth, emotional well-being and social bonding, according to Jacqueline Harding, Ph.D., an early childhood expert at Middlesex University in London. In her book, "The Brain That Loves to Laugh," Harding argues that joy is a complex biological phenomenon that helps children navigate...

Fox News 2d ago

Interpretable factorization of clinical questionnaires to identify latent factors of psychopathology

arXiv:2312.07762v3 Announce Type: replace Abstract: Psychiatry research seeks to understand the manifestations of psychopathology in behavior, as measured in questionnaire data, by identifying a small number of latent factors that explain them. While factor analysis is the traditional tool for this purpose, the resulting factors may not be interpretable, and may also be subject to confounding variables. Moreover, missing data are common, and explicit imputation is often required.

arXiv CS 2d ago

Dimensional Arousal and Categorical Gaze Instability: Uncoupling the Baseline Oculomotor Phenotypes of Autism and ADHD

Background: Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) share substantial clinical and physiological overlap. While naturalistic and sensory-driven paradigms increasingly capture evoked neurophysiological responses, the intrinsic baseline physiology of these conditions remains poorly defined. We aimed to characterize resting-state autonomic arousal and oculomotor stability across the ASD-ADHD spectrum using both continuous (RDoC) and categorical (DSM-5)...

bioRxiv 11d ago

Stimulus-response correlation analysis dissociates spatiotemporal cortical networks supporting speech production

Introduction: Understanding the spatiotemporal distribution of cortical activation during language production is a central question in cognitive neuroscience with broad clinical applications. High spatial/temporal resolution recording over multiple brain regions and specific psycholinguistic manipulations with testable behavioral predictions are necessary to separate neural variance attributable to processing stages. Objective: We combine a delayed naming paradigm with intracranial...

bioRxiv 8d ago

Anguished Parents, Crying Doctors: Life Amid Utah’s Measles Outbreak

Ben Dowse hadn’t expected to treat measles when he became a doctor, but there he was, examining a newborn exposed to the virus in the womb. The infected mother had given birth just hours earlier. The hospital had alerted Dowse to the case before delivery, and he’d braced himself for the worst.

Wired 1d ago

3 new Ebola vaccines are being fast-tracked amid the current outbreak — when could they be ready?

3 new Ebola vaccines are being fast-tracked amid the current outbreak — when could they be ready? The Bundibugyo virus driving the current Ebola outbreak has no approved vaccine, but researchers are leveraging decades of vaccine innovation in an effort to change that. The Ebola outbreak in Central Africa was declared a public health emergency of international concern in May, and since then, over 900 suspected cases and 200 deaths have been reported in the Democratic Republic of the Congo...

Live Science 22h ago

Mel B shares fun details from her hen do and incredible new nickname

Mel B shares fun details from her hen do and incredible new nickname EXCLUSIVE: Mel B is on cloud nine since marrying her husband Rory McPhee - and now she has opened up about her new life in the country and some of her more surprising hobbies Dancing her way to happiness with her new husband, Mel B has everything she 'really, really wants' and is full of good advice on living your best life. Back in the hot seat this week, alongside Simon Cowell, she is judging her eighth season of...

Daily Mirror 3d ago

Worried about the next heatwave? How southern Europeans keep their homes cool without air con

I moved to Sicily from the UK - here’s what I’ve learnt about keeping your home cool during a heatwave. If you had to work indoors or be at home with small children during the record-breaking May heatwave, you’ll know what I’m talking about. Homes in northern Europe, where the heatwave struck, are built to keep the heat in, not let it out.

Euronews 3d ago