DBMC-aNOMAly: Asynchronous NOMA with Pilot-Symbol Optimization Protocol for Diffusion-Based Molecular Communication Networks

arXiv:2512.07317v2 Announce Type: replace Abstract: Multiple access (MA) schemes can enable cooperation between multiple nodes in future diffusion-based molecular communication (DBMC) networks. Non-orthogonal MA for DBMC networks (DBMC-NOMA) is a promising option for efficient simultaneous MA using a single molecule type. This paper studies parameter optimization and bit error probability (BEP) reduction for asynchronous DBMC-NOMA. First, we analytically derive the associated BEP and compare DBMCNOMA with time-division and molecule-division MA. We show that asynchronous offsets can improve performance, and the upper-bound performance can be approached under almost all considered conditions by avoiding a small set of worst-case offset configurations, for which we propose and characterize a dedicated avoidance mechanism. We then propose DBMCaNOMAly, a pilot-symbol-based optimization protocol for asynchronous DBMC-NOMA, and evaluate it using Monte Carlo simulations. DBMC-aNOMAly provides robust BEP reduction across different network sizes and noise levels, under sampling jitter, and under changing runtime conditions, outperforming protocols from previous work. An end-to-end efficiency analysis further shows that these gains translate into increased net throughput after compensating for the pilot overhead. DBMCaNOMAly uses simple operations such as comparisons and additions that are compatible with chemical reaction networks, motivating future realistic modeling of the protocol.