Medicinal plants yield carbon nanoparticles that glow red and flag toxic metals

Medicinal plants yield carbon nanoparticles that glow red and flag toxic metals Stephanie Baum Scientific Editor Robert Egan Associate Editor What do iron, lead and nickel have in common? These heavy metals are an indispensable part of many industries. However, they also share a dark reality: They are serious environmental and public health threats. Every day, they find their way into the atmosphere and water bodies through industrial activities, mining and urban waste. Heavy metals are highly toxic, do not break down naturally and tend to build up in the tissues of living organisms over time. A recent story on the website of Harvard T.H. Chan School of Public Health highlighted that emissions of such heavy metals from power plants could have severe health impacts, including inflammation, airway constriction, blood clotting and cardiac stress. Detecting these contaminants, which is essential for tackling them effectively, often requires sophisticated equipment and expensive testing procedures. Medicinal plants offer a clue What if one promising solution starts with common medicinal plants that are very familiar in Indian homes and have been valued for generations? Researchers from the Indian Institute of Technology Gandhinagar (IITGN) used jamun (Syzygium cumini), tulsi (Ocimum sanctum), neem (Azadirachta indica), guava (Psidium guajava) and curry leaf tree (Bergera koenigii) and presented a simple, time-efficient approach to developing highly sensitive, eco-friendly carbon nanoparticles (CNPs). These plants were selected based on features such as antioxidant and anticancer properties. Their study is published in Nano Express. What are CNPs? They are promising materials with applications in fields such as metal ion detection, bioimaging and antimicrobial activity, among others. CNPs contain nanosized carbon elements, with generally excellent ability to safely interact with living tissue (biocompatibility) and low toxicity. Due to the increasing emphasis on green approaches in recent times, natural and renewable sources such as fruits, vegetables and plant leaves are being employed to generate CNPs. This is an effort to minimize costs, energy-intensive processing and the use of hazardous chemicals. Toward this objective, the team used a rapid microwave-assisted method to generate CNPs with enhanced sensitivity and performance. How the nanoparticles performed All five types of CNPs turned bright red (fluorescence) under UV light. Upon interacting with these CNPs, specific heavy metal ions acted as quenchers and decreased the intensity of the fluorescence they emitted. This feature is an effective tool to detect pollutants. The researchers found that guava-derived CNPs showed sensitivity toward nickel ions, and neem-derived and jamun-derived ones toward iron ions (ferrous ions for the former and ferric ions for the latter). Tulsi-derived CNPs were capable of detecting iron (ferrous ions) and lead ions. "Fascinatingly, the decrease in fluorescence intensity became more pronounced with increasing heavy metal ion concentration. The curry-leaf-derived CNPs did not show this behavior, which could be attributed to factors such as their nonselectivity toward the metal ions used in this study," remarked Parul Singh, a final-year Ph.D. student in the Department of Electrical Engineering at IIT Gandhinagar. Beyond sensing, the plant-derived CNPs also exhibited strong antioxidant activity, following the order of jamun being better than tulsi, followed by guava, neem and curry leaf, respectively. Antioxidants help neutralize unstable molecules known as free radicals, which are associated with conditions such as cellular damage, aging and several diseases. The researchers used two free radicals and found that their violet and blue-green color turned light yellow upon exposure to the CNPs, indicating the presence of antioxidant behavior. Further, biocompatibility assessments revealed minimal toxicity of these CNPs to a type of cell line at low concentrations, with tulsi-derived CNPs being the most compatible. These findings suggest their potential for diagnostic and therapeutic applications. According to Jhuma Saha, "Our work shows that components from medicinal plants can serve as building blocks for nanomaterials with optical, sensing and biomedical capabilities. Future research is needed to explore the scalability of our synthesis technique and the practical use of our CNPs in environmental remediation and biological applications." Saha is an assistant professor in the Department of Electrical Engineering at IIT Gandhinagar. The team also included Dhiraj Bhatia, Mukesh Danka, Hitasha Vithalani, Aniruddha Dan and Nihal Singh from the Department of Biological Sciences and Engineering, and Padma Priya Kannan from the Department of Materials Science and Engineering. As we observe World Environment Day and World Oceans Day in June, such studies highlight how sustainable innovations can contribute to cleaner ecosystems. This research aligns with the Government of India's Mission on Nano Science and Technology (developing nanotechnology-based applications) and Mission LiFE (protecting the environment). Developing CNPs from commonly available plants mirrors the vision of Atmanirbhar Bharat, which emphasizes homegrown solutions. The study also resonates with the United Nations' Sustainable Development Goal 6 (sustainable management of clean water and sanitation) and Goal 9 (Industry, Innovation and Infrastructure). More information Parul Singh et al, Comparative study of medicinal-plant-derived carbon nanoparticles: green synthesis, antioxidant behavior, and metal-ion sensing, Nano Express (2026). DOI: 10.1088/2632-959x/ae3d50 Provided by Indian Institute of Technology Gandhinagar