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Decoding of one of nature's largest enzymes reveals electron flow behind biological methane production

Decoding of one of nature's largest enzymes reveals electron flow behind biological methane production
Phys.org Wednesday 08 July 2026, 21:40 UTC 1 min read
Key Points

A research team at Marburg University has investigated one of the largest enzyme complexes found in nature to date and deciphered its remarkable structure. Under the supervision of Dr. Jan Schuller, Ph.D. student Sophia Paul from the Center for Synthetic Microbiology (SYNMIKRO) was able to characterize the so-called heterodisulfide reductase super-assembly in detail. The results of the study are now published in the journal Nature.

A research team at Marburg University has investigated one of the largest enzyme complexes found in nature to date and deciphered its remarkable structure. Under the supervision of Dr. Jan Schuller, Ph.D. student Sophia Paul from the Center for Synthetic Microbiology (SYNMIKRO) was able to characterize the so-called heterodisulfide reductase super-assembly in detail. The results of the study are now published in the journal Nature. They show how a molecular "giant" comprising hundreds of building blocks enables energy production in microorganisms.
Marburg University (ORG) Jan Schuller (PERSON) Ph.D. (PERSON) Sophia Paul (PERSON) the Center for Synthetic Microbiology (ORG) SYNMIKRO (ORG)
Originally published by Phys.org Read original →

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