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First PLP-dependent enzyme that influences bacterial protein production discovered

First PLP-dependent enzyme that influences bacterial protein production discovered
Phys.org Thursday 10 September 2026, 19:20 UTC 1 min read
Key Points

Researchers from the Singapore-MIT Alliance for Research & Technology's (SMART) Antimicrobial Resistance (AMR) interdisciplinary research group, alongside collaborators from Massachusetts Institute of Technology (MIT), Nanyang Technological University (NTU Singapore), and institutions in the United States, Poland and France, have discovered aminovaleramididine synthetase (AvaS), the first identified pyridoxal phosphate (PLP)-dependent enzyme responsible for producing a chemical modification...

Researchers from the Singapore-MIT Alliance for Research & Technology's (SMART) Antimicrobial Resistance (AMR) interdisciplinary research group, alongside collaborators from Massachusetts Institute of Technology (MIT), Nanyang Technological University (NTU Singapore), and institutions in the United States, Poland and France, have discovered aminovaleramididine synthetase (AvaS), the first identified pyridoxal phosphate (PLP)-dependent enzyme responsible for producing a chemical modification linked to how bacteria respond to metabolic stress.
the Singapore-MIT Alliance for Research & Technology's (ORG) AMR (ORG) Massachusetts Institute of Technology (ORG) MIT (ORG) Nanyang Technological University (ORG) Singapore (LOCATION) the United States (LOCATION) Poland (LOCATION) France (LOCATION)
Originally published by Phys.org Read original →

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