Inactives watch: Collins and Flowers ruled out, Burrow and Nacua questionable

Whom should you start? Whom should you sit? To help you set your fantasy football lineups and avoid starting an offensive player who won't be in the lineup, we'll post fantasy-relevant updates and analysis here as NFL teams release their official inactives lists. Official Sunday inactives should begin coming in approximately 90 minutes before the scheduled kickoff times: around 11:30 a.m. ET for the early games and 2:30 p.m. ET for the late-afternoon games. Refresh often for the latest information. Don't forget to check these out: Mike Clay's Playbook | Week 2 Buzz Week 2 Rankings | Matchup rankings for Week 2 Biggest concerns heading into Week 2 Players with early starts Joe Burrow, QB, Bengals (back): Burrow is dealing with back soreness and is listed as questionable but is expected to start. The quarterback stated that it would be "ridiculous" if the injury caused him to miss Week 2. Even in a tough matchup like the Texans, Burrow is a fantasy QB1. If you want to avoid the matchup, Jaxson Dart and Brock Purdy are realistic options that a fantasy manager could have backing up Burrow. If you're skittish, those two could be started over him. However, for most of you, the choice should be to ride with Burrow. TreVeyon Henderson, RB, Patriots (ankle): After missing the Patriots' opener because of an ankle injury, Henderson returned to practice this week and says he is "ready to go" for Week 2. Henderson will share work in the backfield with Rhamondre Stevenson. However, he is the more explosive option and therefore brings more fantasy upside. Henderson can be played over Quinshon Judkins, MarShawn Lloyd, Tony Pollard, J.K. Dobbins, Rico Dowdle, Blake Corum, Kenny Gainwell and Jonathon Brooks. Jalen Coker, WR, Panthers (ankle): After a huge Week 1 performance, Coker was limited in practice to start the week because of an ankle injury. He was able to log a full practice Friday and was removed from the injury report, meaning he will play in Week 2. While the Panthers will not often have "scorefests" like they did in Week 1, Coker's usage jumps off the screen. He saw nine targets -- three of the deep variety -- and finished with 138 yards and a touchdown, while narrowly missing a second score. Coker is a high upside WR3. You can feel comfortable playing him over DK Metcalf, Michael Pittman Jr, Alec Pierce, Marvin Harrison Jr and Chris Godwin Jr. Alvin Kamara, RB, Saints (knee): Kamara has "moved well" at practice and Kellen Moore has said he should play this week. He is a flex option that brings some PPR upside, but also some risk as we do not know how much work he will see. If he plays, it would be a bit of a thorn in the side of Travis Etienne Jr., who saw nine targets in Week 1. Players with late starts Brock Bowers, TE, Raiders (knee): Bowers returned to practice Friday after having undergone meniscus surgery prior to Week 1. Bowers is doubtful to play in Week 2. Still, if he does get the green light, he should be started -- even if he is limited. If he sits, some replacement options are Dalton Schultz, Juwan Johnson and Michael Mayer. Mayer saw a team-high seven targets last week in Bowers' absence. Ladd McConkey, WR, Chargers (ribs): After leaving Week 1's game early, McConkey didn't practice until Friday. He is questionable but trending toward being available for Week 2. If he were to sit, it would mean more opportunity for Quentin Johnston, who would still fall in the high-risk, high-reward WR3/flex range. If fantasy managers need streamers to fill in, some options are Coker, both Caleb and DeMario Douglas, Vele and Dontayvion Wicks. Brian Thomas Jr, WR, Jaguars (shoulder): After he had been limited in practice this week, Thomas was elevated to full Friday and taken off the injury report. He'll face a tough Broncos secondary and could line up against Pat Surtain II. Thomas saw just three targets in Week 1 and, given the matchup, the floor here is low. Starting him this week is likely hoping for a big play. Some options to play instead are Diggs, Coker, Johnston and Jordan Addison. George Kittle, TE, 49ers (Achilles): Kittle was elevated to full practice after being limited to start the week. This seems like something fantasy managers might have to get used to early on as the veteran is returning from a severe injury. He has been removed from the injury report and will suit up in Week 2. However, he was limited to just 47% of snaps and saw just five targets in Week 1. That said, as time goes on, his usage should gradually increase. Kaelon Black, RB, 49ers (groin): The rookie back who was added in a bunch of fantasy leagues this week was added to the injury report on Thursday. He was limited on Friday and was listed as questionable for Week 2. A late-week status change is never a good sign for Sunday availability, but reports are coming in that he is now expected to play. Black will not likely be started in many fantasy leagues regardless of his status, but a banged-up backup likely means even more carries for Christian McCaffrey. Players on Monday night Puka Nacua, WR, Rams (hip): The superstar receiver is dealing with a hip injury that has held him out of practice this week. He is questionable and likely to be a game-time decision for Monday Night against the Giants. Nacua is impactful enough to risk using him, but with it being a Monday game, fantasy managers need to have a pivot option in case he sits. Malachi Fields would be my preferred option, with Terrance Ferguson also an option if you put Nacua in your flex spot. Other options are Tutu Atwell, Darnell Mooney and Jordan Whittington. Ruled out before Sunday Zay Flowers, WR, Ravens (hamstring): Flowers has been officially ruled out after suffering a hamstring injury in Week 1. He was on his way to a monstrous performance when he exited. He did return to the practice field Friday, which hopefully indicates this will not be a lengthy absence. With Flowers and Ja'Kobi Lane out, Rashod Bateman should be the No. 1 WR option for Lamar Jackson and would bring upside for fantasy, even if the floor is low. Mark Andrews should be started as a TE1. Nico Collins, WR, Texans (hamstring): Collins missed practice this week because of a hamstring injury and has been ruled out for Week 2. For the Texans, Kayshon Boutte and Schultz should see the biggest volume increase. Schultz should be started as a TE1, while Boutte is a big play-reliant flex option. A.J. Brown, WR, Patriots (ankle): Brown landed on IR because of a high-ankle sprain that reportedly could keep him out for six weeks. Fantasy managers also need to worry about a ramp-up period when he eventually returns. In the meantime, you need a plan to help you stay afloat without the early-round WR. Michael Pittman Jr., WR, Steelers (foot): Pittman missed practice all week and has been ruled out for Week 2. His absence likely leads to another game of high volume for Metcalf, who saw 10 targets in Week 1, including five deep. Metcalf is a high-risk, high reward WR3 or flex option as Pittman being out could potentially mean shadow coverage by Christian Gonzalez. For those in need of replacement options for Pittman, some that may be available are Jalen Coker, Caleb Douglas, Devaughn Vele, plus a sleeper for this week -- DeMario Douglas. Kyler Murray, QB, Vikings (concussion): Murray has been ruled out for Week 2. It's unfortunate timing considering the fantastic matchup here against the Bears. With Murray out, Carson Wentz becomes one of the top streaming options of the week. I would play him over Baker Mayfield, Bryce Young, C.J. Stroud and Daniel Jones. Jordan Mason, RB, Vikings (thumb): Mason was placed on IR this week because of a fractured thumb and will miss a minimum of four games. In his absence, Aaron Jones Sr. should handle the bulk of the team's backfield work, placing him in the RB2 range until Mason returns. Sam Darnold, QB, Seahawks (glute): The Super Bowl champion will not play in Week 2's game against the Cardinals. There is good news here, as the Seahawks did not place him on IR, indicating they think he can return sooner than the mandatory four games. Some streaming replacements for Week 2 are Malik Willis, Tyler Shough and Wentz. Michael Penix Jr., QB, Falcons (knee): Penix has been ruled out for Week 2. Tua Tagovailoa is doubtful for Week 2 because of the oblique injury that also cost him Week 1. Kevin Stefanski has been noncommittal on his starting QB, but the expectation is that Cooper Rush will be under center. It's very difficult to trust any Falcons player not named Bijan Robinson. Drake London would still fall in WR3 territory but I would rather play Christian Watson, Terry McLaurin, Tetairoa McMillan or Mike Evans. Kyle Pitts Sr., who had only one target in Week 1, is a sit this week. De'Zhaun Stribling, WR, 49ers (ankle): The rookie sustained a severe ankle injury in Australia that required surgery. He was placed on IR and reportedly could miss as many as 10 weeks. Unfortunately, that means he can be dropped in leagues that do not have IR spots. In his absence, expect Demarcus Robinson to get consistent playing time. Ja'Kobi Lane, WR, Ravens (wrist): Another rookie receiver who put together an impressive preseason, Lane fractured his wrist and was placed on IR. He will miss at least four games. Bateman should get opportunities as the Ravens' WR2 while the rookie is sidelined. Chig Okonkwo, TE, Commanders (hamstring): Okonkwo was gaining steam as a sleeper this week, but unfortunately he will be out because of a hamstring injury. For those who were planning on streaming him, some other options at tight end include Schultz, Mayer and Juwan Johnson.