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Water-stable catalyst could bring carbon-bond chemistry closer to use in living cells

Water-stable catalyst could bring carbon-bond chemistry closer to use in living cells
Phys.org Monday 28 September 2026, 21:20 UTC 1 min read
Key Points

Olefin metathesis is one of the most important reactions in organic chemistry for forming carbon–carbon bonds—for example, in the production of pharmaceuticals, plastics and complex natural products. However, previous ruthenium catalysts that enable this reaction have faced a major challenge: They rapidly degrade in aqueous or biological environments, making their use in natural systems such as cells or blood extremely difficult.

Olefin metathesis is one of the most important reactions in organic chemistry for forming carbon–carbon bonds—for example, in the production of pharmaceuticals, plastics and complex natural products. However, previous ruthenium catalysts that enable this reaction have faced a major challenge: They rapidly degrade in aqueous or biological environments, making their use in natural systems such as cells or blood extremely difficult.
Originally published by Phys.org Read original →

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