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Mutation-dependent responses to sleep and exercise in clonal haematopoiesis

Abstract Clonal haematopoiesis (CH) activates inflammation and increases the risk of atherosclerosis1,2. Whether lifestyle alters CH clone expansion or the phenotypic programming of CH mutant cells, thereby affecting atherosclerosis, is unknown. Here, in humans and mice and across mutations in Jak2, Tet2, Trp53 and Dnmt3a, we demonstrate mutation-dependent responses to sleep and exercise in CH and show that mutant cells are uniquely sensitive to lifestyle.

Nature 20h ago

MCWS 2026: Field for Omaha is set with OU taking the last spot

Country roads, take us to Omaha! The field for the 2026 Men's College World Series is set with all eight spots secured. No. 7 Alabama claimed the most recent spot after beating St. John's 7-2 in the Tuscaloosa Super Regional.

ESPN 1d ago

Men's boxing pound-for-pound rankings: Bivol is ba...

Unified light heavyweight champion Dmitry Bivol defeated Michael Eifert by unanimous decision on May 30 in Ekaterinburg, Russia, in his first fight after a 15-month layoff following back surgery. Bivol had last fought in February 2025, when he avenged his loss to Artur Beterbiev with a majority decision victory to unify all four major belts and become the undisputed champion at 175 pounds. Two months later, Bivol relinquished the WBC title to pursue a trilogy bout with Beterbiev rather than...

ESPN 7d ago

Friday OTT releases this week (June 1 - 5): Madhuri Dixit's 'Maa Behen', Karisma Kapoor's 'Brown', 'Euphoria' Season 3 finale and more

Streaming platforms are pulling out all the stops in the first week of June, with an exciting mix of comedy, thrillers, family dramas and documentaries up for grabs. Madhuri Dixit makes a dark comedy comeback, the Mishra family returns to screens, and Karisma Kapoor makes her much-awaited OTT comeback, making it one of the busiest weeks for binge-watchers. ‘Maa Behen’ Platform: Netflix Release Date: June 4 'Maa Behen', directed by Suresh Triveni, stars Madhuri Dixit, Triptii Dimri and Dharna...

Times of India 5d ago

Women's boxing pound-for-pound rankings: Where doe...

Amanda Serrano further cemented her place among the best current pound-for-pound fighters with a dominant second-round TKO victory over Cheyenne Hanson on Saturday. The win tied her with Christy Martin for the women's record of 32 knockouts. The victory moved Serrano (49-4-1) closer to the 50-win milestone, another achievement in a career already filled with historic accomplishments.

ESPN 7d ago

Which sparkling water is the best?

The Sparkling Water Report three minds and gullets looking for the winning bubbles With my friends Manuel and Aurélien, also friends of the fizz, we set out to find which sparkling water is the best one. We limited ourselves to ones that you could readily buy in Paris, up to the limit of what we could carry. This means 14 waters, blind tested: each water was poured in an opaque glass associated to a number, the glasses were then shuffled and turned facing opposite of the drinkers.

Hacker News 7d ago

Ionization energies for Rydberg $^4 \mathrm{He}$ ($1snp\,^{1,3}P$) states using the correlated B-spline basis function method

Announce Type: new Abstract: We extend the correlated B-spline basis function (C-BSBF) method to high-precision calculations of the ionization energies of helium Rydberg $n^{1,3}P$ states ($n=24$--$35$). Using a unified basis set, we evaluate nonrelativistic energies, relativistic corrections of order $m\alpha^4$ (including finite-mass recoil), QED contributions of order $m\alpha^5$, and partial $m\alpha^6$ terms (singlet-triplet mixing, one- and two-loop radiative corrections). The...

arXiv Physics 6d ago

Ionization energies for Rydberg $^4 \mathrm{He}$ ($1snp\,^{1,3}P$) states using the correlated B-spline basis function method

arXiv:2606.04768v2 Announce Type: replace Abstract: We extend the correlated B-spline basis function (C-BSBF) method to high-precision calculations of the ionization energies of helium Rydberg $n^{1,3}P$ states ($n=24$--$35$). Using a unified basis set, we evaluate nonrelativistic energies, relativistic corrections of order $m\alpha^4$ (including finite-mass recoil), QED contributions of order $m\alpha^5$, and partial $m\alpha^6$ terms (singlet-triplet mixing, one- and two-loop radiative...

arXiv Physics 2d ago

Belmont Stakes 2026 at Saratoga Race Course: Best bets, exotics, 'Pick 5' for the Grade 1 stakes races

This will be the final of three consecutive years that the Belmont Stakes will run at the mecca of horse racing: the Saratoga Race Course. Traditionally held at Belmont Park, the third jewel of horse racing’s Triple Crown has been held in Saratoga during Belmont's renovations and will return to its original home next year. As you probably already know, we won’t get a Triple Crown winner.

Fox News 4d ago

Piastri hunting Monaco silverware to mark historic F1 milestone

Oscar Piastri seeking Monaco success as McLaren marks 1,000 F1 grands prix Fri 5 Jun 2026 at 4:56am In short: McLaren will start its 1,000th Formula 1 grand prix this weekend in Monaco. Australian driver Oscar Piastri enters the Monaco Grand Prix sitting sixth in the drivers' standings. ABC Sport will have a live blog of the Formula 1 Monaco Grand Prix on Sunday, June 7 from 9pm AEST On an historic occasion for one of Formula 1's most storied teams, Oscar Piastri is hoping to add silverware...

ABC Australia 6d ago