ABR
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Related Articles from SNS
Very Early Cortical Auditory Responses to Speech in Humans
A foundational measure of the auditory system's ability to process sound correctly is the auditory brainstem response (ABR) and middle latency response (MLR) complex, but how they vary with stimulus complexity and behavioral relevance is not well understood. To address these issues, we recorded noninvasive electromagnetic temporal response functions (TRFs) in healthy, young adults listening to both clicks and naturalistic speech. Through a source analysis of the responses, we found that the...
Central auditory decline precedes cochlear deficits in a D-galactose mimetic model of aging
Age-related hearing loss reflects a mixture of concurrent peripheral cochlear and central auditory pathway degeneration. Disentangling their relative contributions has remained challenging because both decline together with natural aging. Here, we used systemic D-galactose (D-gal) administration to selectively accelerate central auditory aging while preserving peripheral cochlear function.
Otoprotective effect of MnTBAP in cisplatin-induced hearing loss
Objective: Cisplatin, a life-saving chemotherapeutic drug, causes ototoxicity. Although sodium thiosulfate is used to prevent ototoxicity in pediatric patients, no other intervention has been approved for clinical use against cisplatin-induced hearing loss. Hence, there is an urgent need to identify drugs that prevent cisplatin ototoxicity.