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Adjoint-based Perfusion Estimation from Dynamic Contrast-Enhanced Ultrasound: Advection-Diffusion and Two-Compartment Models

Announce Type: new Abstract: Tumor perfusion and vascular properties are important determinants of a cancer's response to therapy. In this paper, we discuss the estimation of spatially varying blood flow velocities and perfusion parameters from time-resolved contrast agent concentration data. We compare a standard parabolic advection-diffusion model against a two-compartment model governed by a coupled system of hyperbolic advection-reaction equations, which is physiologically more sound.

arXiv CS 2d ago

When can a neural operator replace a coarse solve? Architectural principles for two-level preconditioning

arXiv:2605.19867v2 Announce Type: replace Abstract: Neural operators are increasingly used as accelerators inside classical numerical methods, but it is rarely clear which architectural ingredients matter for which application. We answer this question for one important use case: the coarse-space correction inside a two-level preconditioner for discretised linear partial differential equations.

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APIC: Amortized Physics-Informed Calibration using Neural Processes

Announce Type: new Abstract: Physics models are inherently imperfect due to misspecified or missing mechanisms, resulting in systematic discrepancies between model predictions and real-world observations. The Kennedy-O'Hagan (KOH) framework addresses this issue through explicit discrepancy modeling. However, its non-amortized, per-instance formulation limits scalability across families of related systems.

arXiv CS 7d ago

VITO: Vascular Geometry and Blood Flow Estimation Using Inverse Topology Optimization

arXiv:2606.05487v1 Announce Type: new Abstract: Computed Tomography Angiography (CTA) is widely used to reconstruct vascular geometry from projection measurements, with conventional approaches such as Filtered Back-Projection (FBP) and Iterative Reconstruction (IR) forming the clinical standard. Blood flow is subsequently estimated through Computational Fluid Dynamics (CFD) simulations, which require vascular geometry and boundary conditions to be specified a priori.

arXiv CS 5d ago