Alkaline
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Can alkaline water actually improve your health? Experts separate fact from fiction
Alkaline water has entered the conversation as an arguable alternative to regular drinking water. Numerous celebrities, including Gwyneth Paltrow, Mark Wahlberg and Jennifer Aniston, have touted alkaline water in brand campaigns — but is there a real benefit? Experts report that the science is uncertain.
Viral Nuclease Inhibitors: Small molecule disruptors of the UL12 alkaline nuclease display broad anti-herpes virus activity
Herpes simplex virus-1 (HSV-1) UL12 gene encodes a well-conserved 5' [->] 3' alkaline exonuclease. UL12 collaborates with the HSV single-strand DNA binding protein ICP8 to mediate recombination-dependent replication of viral DNA and is essential for the production of DNA that can be packaged into infectious virus.
Foundational characterization of tomato fruit RALF peptides reveals structural and functional specialization within the SlRALF
Rapid Alkalinization Factor (RALF) peptides regulate plant growth and cell wall signaling, but their roles in fruit development remain unclear. Here, we characterized tomato (Solanum lycopersicum) fruit-associated RALF peptides and their interactions with leucine-rich repeat extensins (LRXs). Expression analyses identified SlRALF5, SlRALF7, and SlRALF10 as the main fruit-expressed RALFs.
Variational quantum algorithm for anion exchange across electrolyzer membrane
arXiv:2512.01120v2 Announce Type: replace Abstract: We present a variational quantum algorithm that solves the one-dimensional diffusion problem with a space-dependent diffusion constant $D(x)$. This problem is relevant for the exchange of hydroxide ions across a two-layer membrane in an alkaline electrolyzer, where the concentration of OH$^-$ ion determines the chemical stability for longer time periods. We use $16$ to $64$ grid points across the membrane, resulting from $n=4$ to 6 data...
Environmental engineers reshape understanding of airborne pollution particles
Environmental engineers reshape understanding of airborne pollution particles Gaby Clark Scientific Editor Robert Egan Associate Editor From sizzling bacon in the kitchen to wildfire smoke in the sky, cooking and pollution release microscopic particles that affect humans' health, the air they breathe, and even weather and climate. New research from Virginia Tech is poised to upend how scientists think about the structure of these tiny airborne droplets and what that means for predictions...
Nitric oxide overload jams plant immune signals, researchers find
Nitric oxide overload jams plant immune signals, researchers find Gaby Clark Scientific Editor Robert Egan Associate Editor A new study from the University of Kentucky Martin-Gatton College of Agriculture, Food and Environment (CAFE) helps explain how plants can lose track of their own disease warnings. Plants do not have blood, nerves or immune cells like people do, but they still have ways to protect themselves. When one leaf is attacked by a pathogen, the plant can send warning signals to...
Fifty-year protein mystery breaks open as acid-driven water loss comes into view
Fifty-year protein mystery breaks open as acid-driven water loss comes into view Sadie Harley Scientific Editor Robert Egan Associate Editor Proteins systematically lose their protective hydration shell when their environment becomes more acidic. Until recently, this was just a theory. State-of-the-art imaging techniques have helped researchers at Martin Luther University Halle-Wittenberg (MLU) directly observe this process for the first time at the level of the individual water molecule.
Programmable chemistry unlocks drugs only in target cells, aiming to cut side effects
Programmable chemistry unlocks drugs only in target cells, aiming to cut side effects Gaby Clark Scientific Editor Robert Egan Associate Editor Potent drugs like chemotherapy can be life-saving, but often with life-threatening side effects. Notably, they can be indiscriminate, killing both cancer cells and healthy cells in one swoop. Increasing a drug's on-target efficiency can reduce side effects and enable healthier outcomes for patients.
SOD1 Catalyses Thiol Oxidation to Thiosulfinates
Cu/Zn superoxide dismutase (SOD1) is canonically regarded as a superoxide scavenging antioxidant yet is paradoxically associated with multiple diseases. Here, we show that SOD1 catalyzes thiol oxidation to thiosulfinates (RS(O)SR), revealing a previously unrecognized copper mediated oxidant forming reaction in biology. Steady state kinetics demonstrate robust, O2 dependent thiol consumption, and ATR FTIR spectra of the SOD1-cysteine reaction display S--O bands ({approx}1042/1169 cm-1)...
We can predict space weather—what if we could also stop it?
We can predict space weather—what if we could also stop it? Stephanie Baum Scientific Editor Robert Egan Associate Editor The weather on Earth can get pretty messy sometimes. But in space, it can be wild, and the effects can be far-reaching.