Ancestral Diversity
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Related Articles from SNS
Cellular Complexity and Systemic Immune Profiles across Ancestral Diversity in Thailand and Mainland Southeast Asia
Mainland Southeast Asia (MSEA) remains under-represented in global immunogenomic references despite its extensive genetic heterogeneity. We present the first single-cell immune atlas of an MSEA population, utilizing Thai individuals from the Asian Immune Diversity Atlas (AIDA) as a representative cohort. We demonstrate that the Thai population is highly genetically diverse, reflecting its history as a geographic nexus for Asian admixture.
How migration became a key to World Cup success
How migration became a key to World Cup success Lisa Lock Scientific Editor Andrew Zinin Lead Editor Few would have predicted Morocco's success at the 2022 Fifa World Cup. Heading into the tournament, they were ranked 22nd in the world and had never progressed beyond the round of 16. Yet they beat Belgium, Spain and Portugal—countries that both then and now rank inside the world's top 10—on their way to becoming the first African nation ever to reach the semi-final.
Improving viral protein clustering using both diversified protein profiles and structural information
Viruses are abundant, ancestral and potentially fast-evolving biological entities. As a result, their encoded proteins are diverse and identifying homologous relationships between sequences is as important for phylogeny and functional annotation as it is challenging. Traditional methods group viral proteins by sequence similarity, build HMM profiles for each protein family, and cluster further via profile comparisons.
Whole-genome duplication shaped cell-type evolution in the vertebrate brain
Abstract The complex brains of vertebrates have more cell types than those of their closest relatives. Whole-genome duplications (WGDs) occurred during early vertebrate evolution1, but it is unclear whether the duplicated genes (ohnologues) facilitated cell-type evolution. Here using brain single-cell transcriptomes from five chordates—human2, mouse3, lizard4, lamprey5 and amphioxus—we report that many cell-type families with conserved core transcription factors in vertebrates do not show...
PACE: Post-Causal Entropy Modeling for Learned LiDAR Point Cloud Compression
arXiv:2605.01320v2 Announce Type: replace Abstract: LiDAR point cloud compression is vital for autonomous systems to handle massive data from high-resolution sensors. While learned entropy modeling built upon octree structures yields high compression gains, it faces two critical bottlenecks: 1) prohibitive latency, particularly during decoding, caused by causal, multi-stage context modeling; and 2) a rigid performance-latency trade-off, preventing a single model from adapting to varying...
Tryptophan became part of the universal genetic code post-LUCA
We evaluate whether tryptophan (W), widely thought to be the last of the 20 canonical amino acids added to the genetic code, was already present in the Last Universal Common Ancestor (LUCA). We reconstruct the evolutionary history of tryptophanyl-tRNA synthetase (WRS), the enzyme that attaches W to its tRNA, and the related tyrosyl-tRNA synthetase (YRS). We identify and exclude sequences derived from ancient recombination between archaeal and bacterial YRSs.
Karyotype evolution of angel insects (Zoraptera)
Our study provides the first comprehensive karyotype evolution analysis of the insect order Zoraptera. We present karyotypic descriptions of seven species across two families: Zorotypidae (Usazoros hubbardi and two Zorotypus spp.) and Spiralizoridae (Centrozoros gurneyi, Spiralizoros magnicaudelli, and two Spiralizorose spp.).
Gene ancestries reveal diverse microbial associations during eukaryogenesis
Abstract The origin of eukaryotes remains a central enigma in biology1. Continuing debates agree on the pivotal role of a symbiosis between an alphaproteobacterium and an Asgard archaeon2,3. However, the nature, timing and contributions of other potential bacterial partners4,5,6 and the role of interactions with viruses7,8,9 remain contentious.
Koala population crash came before humans, genomic study reveals
Koala population crash came before humans, genomic study reveals Sadie Harley Scientific Editor Robert Egan Associate Editor A genomic study has reshaped our understanding of the evolutionary history of the koala (Phascolarctos cinereus), revealing the iconic Australian marsupial experienced a severe population decline around 100,000 years ago, before the arrival of humans on the continent. All modern koalas descended from a single ancestral population that survived major climate...
Koala numbers crashed across Australia 100,000 years ago. Global glacial cycles are likely to blame
Koala numbers crashed across Australia 100,000 years ago. Global glacial cycles are likely to blame Lisa Lock Scientific Editor Andrew Zinin Lead Editor It's surprising how easy it is to see a koala every day in Australia's major cities. The cute, gray marsupial can be found on T-shirts, hanging off people's bags and pencils, and decorating any decent souvenir shop.