Andrew G
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From golfing with Trump to the World Cup, Andrew G...
WHEN ANDREW GIULIANI first heard about the job, he called the West Wing. Within a week, he said, he was pitching President Donald Trump on why he was the best choice to lead the federal government's preparations for the World Cup -- and why even though he didn't have any law enforcement experience, he should be put in charge of a coalition of cabinet secretaries, federal law enforcement and intelligence agencies such as the FBI, the NSA and the Department of Homeland Security. Giuliani is...
Whole-genome duplication shaped cell-type evolution in the vertebrate brain
Abstract The complex brains of vertebrates have more cell types than those of their closest relatives. Whole-genome duplications (WGDs) occurred during early vertebrate evolution1, but it is unclear whether the duplicated genes (ohnologues) facilitated cell-type evolution. Here using brain single-cell transcriptomes from five chordates—human2, mouse3, lizard4, lamprey5 and amphioxus—we report that many cell-type families with conserved core transcription factors in vertebrates do not show...
The U.S. Is Winging This Ebola Outbreak
By the time African health officials confirmed the world’s latest Ebola outbreak, the epidemic had already spilled from the Democratic Republic of the Congo into neighboring Uganda. Within two days, the World Health Organization declared the outbreak a public-health emergency of international concern. Less than two weeks later, the potential case count has risen past 1,000, including more than 230 deaths, and 10 other African countries have been designated at risk of being swept into the...
A 5.3-million-year-old deep-sea whale necropolis in the Diamantina Zone
Abstract Whale falls are biodiversity oases at seabeds1,2,3,4,5,6, yet their record from the oceans has remained sparse and fragmentary6,7. Here we report the discovery of a vast whale necropolis in the Diamantina Zone (4,616- to 7,001-m depth), extending about 1,200 km along the sea floor of the southeastern Indian Ocean. This area has a deep and extensive accumulation comprising five modern natural whale-fall communities and 476 fossil cetaceans recorded.
World's largest opioid review finds they often don't work
World's largest opioid review finds they often don't work - Date: - June 9, 2026 - Source: - University of Sydney - Summary: - The largest review ever conducted on opioids for acute pain found that these widely prescribed drugs often deliver only small, short-lived benefits. For many common conditions, including some surgeries and kidney stone pain, opioids performed no better than a placebo.
This drug delayed rheumatoid arthritis for years after treatment ended
This drug delayed rheumatoid arthritis for years after treatment ended - Date: - June 1, 2026 - Source: - King's College London - Summary: - A promising new study suggests rheumatoid arthritis may not be as inevitable as once thought for people at high risk. Researchers found that just one year of treatment with the immune-targeting drug abatacept delayed the onset of rheumatoid arthritis by up to four years, with benefits lasting long after treatment ended. - Share: People at high risk of...
Scientists discover why ozempic may not work for some people
Scientists discover why ozempic may not work for some people A hidden genetic quirk may be making some people surprisingly resistant to the benefits of blockbuster GLP-1 diabetes drugs. - Date: - June 5, 2026 - Source: - Stanford Medicine - Summary: - Scientists have identified genetic variants that may make some people less responsive to GLP-1 drugs used to treat Type 2 diabetes.
Smart surfaces face zero gravity test in boiling heat experiments
Smart surfaces face zero gravity test in boiling heat experiments Lisa Lock Scientific Editor Andrew Zinin Lead Editor A research team led by Davoud Jafari at the University of Twente, in collaboration with the University of Pisa, has completed a series of parabolic flight experiments to investigate advanced smart surfaces under rapidly changing gravity conditions. Conducted aboard the Air Zero G aircraft operated by Novespace, the campaign integrated additive manufacturing, boiling heat...
SIRT7 regulates dosage compensation and safeguards the female X chromosome
Abstract Sirtuins are deacetylases implicated in stress responses and longevity in mammals1,2. Although their differential impact on disease for the two sexes has been noted3,4,5,6,7, the underlying reasons are unclear. Here, using Sirt7 as a model in mice, we examine the mechanisms leading to sex differences and find that Sirt7−/− female mice have decreased fitness throughout their lifespan.
Mitochondria directly interact with the nuclear pore complex
Abstract Mitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic reticulum membranes1, which control pathways including redox and calcium homeostasis2,3. Recent studies have also reported direct mitochondria–nuclear membrane contacts in cancer cells and yeast that promote pro-survival signalling4,5.