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Programmable Assembly of DNA Tetrahedra Bearing Atomically Precise Gold Nanoclusters: Stoichiometric Control and Molecular-Level Characterization

Atomically precise gold nanoclusters (AuNCs) are ultra-small particles composed of ten to hundreds gold atoms and exhibit unique photophysical properties. Significant progress has been made in tuning and extending their luminescence in the near-infrared window through the design of AuNC assemblies. Herein, we report a straightforward method for synthesizing highly pure, programmable DNA tetrahedra functionalized with a controlled number of AuNCs (from one up to four AuNCs).

bioRxiv 1d ago