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KBase Research Agent: Automated Multi-Agent Workflow Construction for Reproducible Genome Analysis

Constructing multi-step bioinformatics workflows, from read quality control through genome assembly to functional annotation, requires expertise in both biology and computational tool selection, creating a bottleneck for scalable and reproducible analysis. We present the KBase Research Agent, a multi-agent system for automating such workflows within the DOE Systems Biology Knowledgebase (KBase). Given a set of sequencing reads and a research objective, the agent constructs an analysis plan...

bioRxiv 6d ago

PDE-Agents: An LLM-Orchestrated Multi-Agent Framework for Automated Finite Element Simulations with Knowledge Graph-Augmented Reasoning

Announce Type: new Abstract: We present PDE-Agents, a multi-agent ecosystem that automates the full lifecycle of partial differential equation (PDE) / finite element method (FEM) simulations through natural-language interaction. Three specialist large language model (LLM) agents (Simulation, Analytics, Database) are orchestrated via a LangGraph supervisor, with a local open-source LLM stack (Qwen3-Coder-Next, Llama 4 Scout) on dual NVIDIA RTX PRO 6000 GPUs. The architecture is...

arXiv Physics 1d ago

An AI Security Agent for University ACMIS: Multi-Vector Threat Detection and Automated Response

Announce Type: new Abstract: University Academic Management Information Systems (ACMIS) are high-value targets for a wide spectrum of security threats including brute-force login attacks, payment fraud, privilege escalation, insider data theft, and academic integrity violations. Traditional rule-based intrusion detection systems are inadequate because many malicious activities are structurally indistinguishable from normal operations. This paper presents an AI-based security agent for ACMIS...

arXiv CS 1d ago

SHIELDS: Automating OS Hardening with Iterative Multi-Agent Remediation

arXiv:2606.05476v1 Announce Type: new Abstract: Security misconfigurations remain a leading cause of OS-level compromise, and manually keeping systems compliant with standards like Defense Information Systems Agency (DISA) Security Technical Implementation Guides (STIGs) is a tedious and expensive process. Existing compliance automation tools can reduce some of this burden, but they depend on static, pre-written corrective actions. In this paper, we introduce SHIELDS, a multi-agent system...

arXiv CS 5d ago

PhysAgent: Automating Physics-Based 4D Synthesis via Trajectory-Grounded Multi-Agent Feedback

Announce Type: new Abstract: Achieving fully automated, physically plausible 3D motion synthesis is a core objective in graphics and generative AI. However, configuring complex environmental force fields still relies entirely on manual expert intervention, creating a severe bottleneck for large-scale simulation data generation. Existing automated methods primarily focus on material optimization and exhibit severe modality gaps and technical flaws when applied to the vastly more complex force...

arXiv CS 1d ago

Online Skill Learning for Web Agents via State-Grounded Dynamic Retrieval

arXiv:2606.04391v1 Announce Type: new Abstract: Language agents increasingly rely on reusable skills to improve multi-step web automation across related tasks. A growing line of work studies online skill learning, where agents continually induce skills from previous task trajectories and reuse them in future tasks on the fly. However, existing methods mainly reuse skills at the task-level: a fixed set of skills is retrieved based on the initial task instruction and then held fixed throughout...

arXiv CS 6d ago

MEnvAgent: Scalable Polyglot Environment Construction for Verifiable Software Engineering

arXiv:2601.22859v3 Announce Type: replace Abstract: The evolution of Large Language Model (LLM) agents for software engineering (SWE) is constrained by the scarcity of verifiable datasets, a bottleneck stemming from the complexity of constructing executable environments across diverse languages. To address this, we introduce MEnvAgent, a Multi-language framework for automated Environment construction that facilitates scalable generation of verifiable task instances. MEnvAgent employs a...

arXiv CS 1d ago

QUARE: Quality-Aware Requirements Analysis through Multi-Agent Dialectical Negotiation

Announce Type: replace Abstract: Automating requirements quality analysis remains challenging because multiple, often conflicting quality attributes must be balanced while preserving stakeholder intent. Existing Large-Language-Model (LLM) approaches predominantly rely on task-oriented decomposition or implicit aggregation, limiting their ability to systematically surface and resolve cross-quality conflicts. We present QUARE (QUality-Aware REquirements Analysis), a multi-agent framework that...

arXiv CS 2d ago