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Contemporary AI lacks the imagination to diverge or negate in science
arXiv:2606.08251v1 Announce Type: new Abstract: Bold projections that artificial intelligence will accelerate scientific discovery have raced ahead of evidence from working scientists, and the field still lacks large-scale, scientist-in-the-loop tests of these claims. Here we mount the largest such evaluation to date and map what AI cannot yet do for science. We invited authors of 121,640 recent preprints across biology, medicine, chemistry, and the social sciences to judge follow-up ideas...
Q&A: Most biology education guidelines lack any connection to society, researchers explain why that's a problem
Q&A: Most biology education guidelines lack any connection to society, researchers explain why that's a problem Sadie Harley Scientific Editor Andrew Zinin Lead Editor Is it a doctor's job to get the best outcomes for their patients or to tell the truth? What happens when these two things are not aligned? These are questions that University of Washington students have to wrangle with in Biol 180: Introductory Biology.
Efficient Synthetic Network Generation via Latent Embedding Reconstruction
Announce Type: cross Abstract: Network data are ubiquitous across the social sciences, biology, and information systems. Generating realistic synthetic network data has broad applications from network simulation to scientific discovery. However, many existing black-box approaches for network generation tend to overfit observed data while overlooking characteristic network structure, and incur substantial computational overhead at scale.
New 3D microscope technology captures high-resolution tissue images at a fraction of the cost
New 3D microscope technology captures high-resolution tissue images at a fraction of the cost Sadie Harley Scientific Editor Robert Egan Associate Editor A team led by Raju Tomer, professor of biological sciences at Columbia University, has created a new design for microscopes and microscope lenses that could push 3D tissue imaging beyond state-of-the-art systems while drastically cutting costs and complexity. Details of the design were published in the journal Nature Biotechnology. Modern...
Small-angle solution scattering: from fundamental theory to practical approximations
arXiv:2606.05007v1 Announce Type: new Abstract: Small-angle scattering (SAS) is widely used in structural biology, soft matter, and colloidal science to probe molecular structures in solution. SAS rests on a single physical principle: wave interference from a distribution of scatterers, averaged over orientations. Yet the theoretical foundations of SAS are spread across the literature, often based on differing notation, definitions, and implicit assumptions.
Eight metabolic niches reveal how ocean microbes recycle carbon worldwide
Eight metabolic niches reveal how ocean microbes recycle carbon worldwide Stephanie Baum Scientific Editor Robert Egan Associate Editor The ocean is full of invisible workers. Trillions of microbes quietly break down carbon-containing organic matter, which helps to regulate Earth's climate. But scientists have long struggled to understand how different microbes contribute to the process.
A new origin story for multicellular life points to physics, not genes alone
A new origin story for multicellular life points to physics, not genes alone Sadie Harley Scientific Editor Robert Egan Associate Editor How did life make the leap from single cells to coordinated, multicellular organisms? And how do genetically identical cells still perform a version of that feat every time an embryo begins to take shape? In a new Perspective paper appearing in the journal Nature Biotechnology, Bren Professor of Biology and Biological Engineering Magdalena Zernicka-Goetz...
'All-in-one' platform developed for multiple trait stacking in crops
'All-in-one' platform developed for multiple trait stacking in crops Gaby Clark Scientific Editor Alexander Pol Deputy Editor A major goal of modern crop breeding is to efficiently combine multiple desirable traits by "stacking" the favorable gene variants (alleles) that contribute to those traits in a single crop variety. However, current strategies are often time-consuming and inefficient. Now, a team led by Gao Caixia at the Institute of Genetics and Developmental Biology of the Chinese...