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Ageing blunts the phospho-proteomic response to resistance exercise in humans
Ageing blunts the adaptive growth response in human skeletal muscle. To define the molecular processes underlying this impairment, we performed unbiased analysis of the phosphoproteome and total proteome in healthy young and old human skeletal muscle following acute resistance exercise (ResEX) and essential amino acid (EAA) ingestion. Ageing led to global suppression of the growth-induced global phosphoproteome, despite intact mTORC1 activation in old muscle.
Jennifer Lopez, Brittany Snow and Emily Blunt turn heads in dazzling gowns on the red carpet
Hollywood's biggest names stunned on different red carpets this week. Stars including Jennifer Lopez and Brittany Snow turned heads when they posed for photos at the Gotham Awards and movie premieres in sparkling gowns. Other celebrities lit up the red carpet at their movie premieres in stunning dresses.
From Sidda to DKS: Congress hopes Karnataka change of guard will blunt anti-incumbency, fill gaps
Congress's surgical operation in Karnataka stems from its estimates of gaps after three years of the Siddaramaiah government and its expectations from DK Shivakumar at the helm, with eyes focused on future political battles - 2028 assembly polls followed by Lok Sabha polls. The transition from Siddaramaiah to Shivakumar is rooted in the informal arrangement that was made at the time of the selection of CM following a keen tussle between the two for the top post. But, sources said, the...
‘Throw age out of the window’: Rabada's blunt take on Sooryavanshi
Kagiso Rabada believes Rajasthan Royals teenager Vaibhav Sooryavanshi's remarkable IPL 2026 campaign has been built on fearless cricket, quick reflexes and an ability to read bowlers earlier than most players his age. The Gujarat Titans pacer showered praise on the 15-year-old after Qualifier 2 on Friday, where Sooryavanshi's stunning 96 went in vain as GT chased down 215 to secure a seven-wicket win and book their place in the IPL 2026 final against Royal Challengers Bengaluru. Sooryavanshi...
'Play according to situation': India coach's blunt message to Rishabh Pant
NEW DELHI: India assistant coach Ryan ten Doeschate on Thursday said Rishabh Pant needs to adapt his batting according to match situations, while also confirming that the wicketkeeper-batter had no issues with losing the Test vice-captaincy. Speaking ahead of India's one-off Test against Afghanistan, which begins on Saturday, ten Doeschate stressed the importance of leadership without a formal role and said Pant's focus should be on making the right decisions based on the situation of the...
'Look at the form': Agarkar's blunt explanation for Suryakumar T20 exit
Chief selector Ajit Agarkar said the Board of Control for Cricket in India's (BCCI) decision to remove Suryakumar Yadav as India's T20I captain was not taken lightly, stressing that selectors reassessed the team's direction after the 2026 T20 World Cup while also considering the next cycle leading up to the 2028 edition. BCCI announced a major change in Indian men's T20I setup on Saturday, handing the captaincy to Shreyas Iyer for the upcoming tours of Ireland and England. Suryakumar not...
Graham Platner’s cocaine brag resurfaces as unearthed posts reveal blunt admission
Graham Platner, the presumptive Democratic nominee for Senate in Maine, bragged in newly resurfaced social media posts about doing hard drugs while on military leave – adding that he had "no regrets" about his past escapades. Platner, a combat veteran of both the Marine Corps and the Army National Guard, claimed in a 2020 Reddit post made under the handle P-Hustle that he was "partying it up" by using drugs while backpacking through Spain on military leave. In a post made that same year, he...
Graham Platner’s cocaine brag resurfaces as unearthed posts reveal blunt admission
Graham Platner, the presumptive Democratic nominee for Senate in Maine, bragged in newly resurfaced social media posts about doing hard drugs while on military leave – adding that he had "no regrets" about his past escapades. Platner, a combat veteran of both the Marine Corps and the Army National Guard, claimed in a 2020 Reddit post made under the handle P-Hustle that he was "partying it up" by using drugs while backpacking through Spain on military leave. In a post made that same year, he...
Liberation of Premier League title can help Arsenal blunt PSG and join Europe’s elite
Title: Arsenal's Premier League title win can help them overcome PSG and join Europe's elite Mikel Arteta must find the balance between newfound freedom and tried-and-tested solidity against Luis Enrique's attacking machineWelcome to Budapest: city of stew, city of pavement squares, city of men in cotton smocks offering brisk muscular relaxation in geothermally heated cubicles. Eleven days on from the profound emotional release of winning the Premier League title it seems fitting Arsenal will approach their season's endgame in a city that is basically perfect for a restorative summer city break.Saturday afternoon at the Puskas Arena already looks like a twin-track event for Mikel Arteta's team, an occasion that changes shape according to the angle from which you see it. On one hand, victory against Paris Saint-Germain in the Champions League final would represent the greatest day in Arsenal's history. On the other, this is an occasion that feels strangely light, fun, celebratory, a free-hit kind of final. Continue reading...
EU Delays Bank Trading-Book Rules to Blunt Wall Street Advantage
The banking district skyline in Frankfurt.