CA3

Sparse-to-dense coding transformation between hippocampal areas CA3 and CA1

Equivalent volitional learning emerges through circuit-specific population dynamics in motor cortex and hippocampus

Learning operates across different brain circuits to associate population activity patterns with desired outcomes, and to enable volitional reactivation of those patterns to control behavior. These circuits differ profoundly in their architecture and dynamical regimes, yet which features of learning are shared across them and which arise from circuit-specific implementations remains unknown. Here, we use a brain-computer interface (BCI) to train mice to modulate the activity of selected...