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New ways to prevent flu revealed in 'accidental' lab breakthrough, study finds
An accidental lab discovery has opened the door to entirely new ways of preventing the flu. While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells, SWNS reported. By targeting the specific molecules the viruses rely on, scientists found that they could block them from entering new cells and halt their replication altogether.5 THINGS YOU NEED TO KNOW BEFORE GETTING YOUR FLU SHOT, ACCORDING...
Scientists found a new Alzheimer’s trigger and a drug that stops it
Scientists found a new Alzheimer’s trigger and a drug that stops it - Date: - June 8, 2026 - Source: - ETH Zurich - Summary: - Researchers have identified a new Alzheimer’s target and created an experimental compound that blocks a damaging process inside brain cells. In mice, the treatment slowed nerve cell loss, reduced Alzheimer’s-related changes, and even appeared to promote healthier aging. - Share: A promising experimental compound developed by researchers at ETH Zurich could offer a...
Memory decline after menopause linked to loss of estrogen production in brain
A largely overlooked space between cells in women’s brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study. Nearly two-thirds of Americans with Alzheimer’s disease (AD) are women, but the reasons why women are more vulnerable are still not fully understood. Scientists have long theorized that the loss of estrogen after menopause may reduce the brain’s natural protection against memory loss and...
Differential Induction of Cancer Cell Death by Root, Leaf, and Flower Extracts derived from Kalanchoe pinnata
Kalanchoe pinnata is a perennial plant that grows wild in tropical regions and is traditionally used as a medicinal plant. Plants of the Kalanchoe genus have been shown to possess several effects, including antibacterial and antihypertensive properties. However, effects such as the induction of apoptosis in cancer cells have not been reported for any substance other than leaf extracts of this plant and remain unexplained.
Mitochondria directly interact with the nuclear pore complex
Abstract Mitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic reticulum membranes1, which control pathways including redox and calcium homeostasis2,3. Recent studies have also reported direct mitochondria–nuclear membrane contacts in cancer cells and yeast that promote pro-survival signalling4,5.
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.
Diagnostic dilemma: Doctors couldn't explain why a boy was bleeding from his eyes, ears and nose
Diagnostic dilemma: Doctors couldn't explain why a boy was bleeding from his eyes, ears and nose A case of a boy who bled from his eyes eventually led doctors to a diagnosis that has been reported fewer than 50 times in the medical literature. The patient: An 11-year-old boy in India The symptoms: The boy's parents brought him to a hospital after he had several episodes of bleeding from his eyes, nose and ears. The episodes, which had occurred for about a month, seemed to start for no...
A prognostic human brain network for diffuse midline glioma
Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.
Mutation-dependent responses to sleep and exercise in clonal haematopoiesis
Abstract Clonal haematopoiesis (CH) activates inflammation and increases the risk of atherosclerosis1,2. Whether lifestyle alters CH clone expansion or the phenotypic programming of CH mutant cells, thereby affecting atherosclerosis, is unknown. Here, in humans and mice and across mutations in Jak2, Tet2, Trp53 and Dnmt3a, we demonstrate mutation-dependent responses to sleep and exercise in CH and show that mutant cells are uniquely sensitive to lifestyle.
Spain detects 111 cases of rare cancer linked to breast implants
The Ministry of Health has confirmed over a hundred cases of this rare cancer linked to breast implants, mostly in women with textured prostheses. The Spanish Agency of Medicines and Medical Devices (Aemps) has confirmed a total of 111 cases of anaplastic large cell lymphoma associated with breast implants (ALCL) up to 2025, a rare type of cancer linked to breast implants. In total, the agency has received 146 suspected reports since it began monitoring this condition in 2012.