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Claude Fable 5

Claude Fable 5 and Claude Mythos 5 Today we’re launching Claude Fable 5: a Mythos-class1 model that we’ve made safe for general use. Fable 5’s capabilities exceed those of any model we’ve ever made generally available.

Hacker News 1d ago

SCI-PRM: A Tool Aware Process Reward Model for Scientific Reasoning Verification

Announce Type: new Abstract: While Process Reward Models (PRMs) have achieved remarkable success in mathematical reasoning, their application in complex scientific domains-such as biology, chemistry, and physics remains largely unexplored. Scientific problems demand not only logical rigor but also factual consistency and the precise usage of domain-specific tools, areas where current models often suffer from hallucinations and lack of verification. In this paper, we first construct...

arXiv CS 6d ago

Contemporary AI lacks the imagination to diverge or negate in science

arXiv:2606.08251v1 Announce Type: new Abstract: Bold projections that artificial intelligence will accelerate scientific discovery have raced ahead of evidence from working scientists, and the field still lacks large-scale, scientist-in-the-loop tests of these claims. Here we mount the largest such evaluation to date and map what AI cannot yet do for science. We invited authors of 121,640 recent preprints across biology, medicine, chemistry, and the social sciences to judge follow-up ideas...

arXiv CS 1d ago

MHT CET 2026 PCB result released at cetcell.mahacet.org: Direct link to download scorecards here

MHT CET 2026 result: The State Common Entrance Test Cell, Maharashtra has announced the Maharashtra Common Entrance Test (MHT CET) 2026 results for the Physics, Chemistry and Biology (PCB) group. Candidates who appeared for the examination can now check and download their scorecards through the official website, cetcell.mahacet.org. To access the MHT CET 2026 PCB result, candidates will need to log in using their registered roll number and password.

Times of India 1d ago

Protein Language Model Embeddings Improve Generalization of Implicit Transfer Operators

Announce Type: replace-cross Abstract: Molecular dynamics (MD) is a central computational tool in physics, chemistry, and biology, enabling quantitative prediction of experimental observables as expectations over high-dimensional molecular distributions such as Boltzmann distributions and transition densities. However, conventional MD is fundamentally limited by the high computational cost required to generate independent samples. Generative molecular dynamics (GenMD) has recently emerged as...

arXiv Physics 9d ago

Protein Language Model Embeddings Improve Generalization of Implicit Transfer Operators

Announce Type: replace Abstract: Molecular dynamics (MD) is a central computational tool in physics, chemistry, and biology, enabling quantitative prediction of experimental observables as expectations over high-dimensional molecular distributions such as Boltzmann distributions and transition densities. However, conventional MD is fundamentally limited by the high computational cost required to generate independent samples. Generative molecular dynamics (GenMD) has recently emerged as an...

arXiv CS 9d ago

Anthropic says these topics are too dangerous to let its Fable 5 model talk about

Anthropic Tuesday publicly released Claude Fable 5, its first "Mythos-class" model that it says surpasses its previous frontier Opus models in overall capabilities. But the model's launch today comes with safeguards designed to prevent it from answering queries on topics like cybersecurity, biology, and chemistry, where the company has publicly worried about its potential impact to "uplift" malicious actors. Anthropic says Fable 5 operates on the "same underlying model" as Mythos 5, which is...

Ars Technica 23h ago

Fish-microbe partnership may influence ocean health by making carbon-trapping minerals

The article discusses a study that explores the relationship between the gut microbes of a fish and global ocean processes. The research suggests that symbiotic bacteria may support calcium carbonate precipitation in the Gulf toadfish, which could have implications for ocean chemistry and the marine carbon cycle. The study, published in PLOS Biology, provides new insight into how marine ecosystems help regulate ocean chemistry and the marine carbon cycle.

Phys.org 11d ago

Programmable chemistry unlocks drugs only in target cells, aiming to cut side effects

Programmable chemistry unlocks drugs only in target cells, aiming to cut side effects Gaby Clark Scientific Editor Robert Egan Associate Editor Potent drugs like chemotherapy can be life-saving, but often with life-threatening side effects. Notably, they can be indiscriminate, killing both cancer cells and healthy cells in one swoop. Increasing a drug's on-target efficiency can reduce side effects and enable healthier outcomes for patients.

Phys.org 6d ago

Want an oxygen-rich atmosphere? Stuff oxygen’s friends in the mantle.

A new study suggests that changes in the subduction of tectonic plates may be linked to increases in Earth's oxygen levels. This process, where plates sink into the Earth's interior, appears to correlate with the timing of oxygen jumps. The research indicates that the chemistry of the solid Earth played a role alongside biological processes in building up the oxygen-rich atmosphere.

Ars Technica 15d ago