CloneSeach

Unbiased identification of responding T cell clones from longitudinal repertoire sequencing with CloneSearch

T cells activate and expand upon interaction with cognate antigen, derived from pathogens or mutated proteins. T cell clones can be identified by their T cell receptor (TCR) which can act as a unique barcode to track their expansion. Longitudinal TCR sequencing can be used to track T cell responses to a large array of stimuli.