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p38 dependent IL-33 responses define a conserved inflammatory programme in mast cells
Interleukin-33 (IL-33) is a key cytokine in mast cell mediated immunity, promoting inflammatory cytokine production without inducing degranulation. Here, we compared IL-33 induced proteomic responses across three mast cell culture systems, Foetal Liver derived Mast Cells (FLMCs), Bone Marrow derived Mast Cells (BMMCs), and Peritoneal Mast Cells (PMCs), using quantitative data-independent acquisition mass spectrometry. Although baseline proteomes were largely conserved across all mast cell...
Democrats navigate a new Graham Platner controversy in Maine’s battleground Senate race
For the Democratic Party, the road to Maine’s Senate primary is paved in dread. All Graham Platner had to do was glide into Tuesday’s election to clinch the state’s Democratic Senate nomination, since Gov. Janet Mills abruptly suspended her campaign in late April. But with each passing day, the divisions inside the party have grown as some lawmakers and activists say they are increasingly alarmed over the breadth and depth of controversies and scandals facing the military veteran.
Trump admin backs off controversial $2B fund, clearing path for stalled GOP immigration bill
The Department of Justice (DOJ) pressed pause on the Trump administration's "anti-weaponization" fund on Monday, giving Senate Republicans runway to hammer through a massive immigration enforcement funding package in the process. The DOJ announced on X that it would abide by a Virginia federal court's order to not move forward with the fund. It comes as Republicans in the upper chamber punted their plan to advance a $72 billion immigration enforcement package over deep concerns about who...
Trump reconsiders $1.8 billion ally compensation fund amid Republican backlash
Trump reconsiders $1.8 billion ally compensation fund amid Republican backlash President Donald Trump was said to be reconsidering a controversial $1.8 billion compensation fund on Monday, created as part of a settlement with the IRS, amid legal challenges and growing opposition from Republicans. The Justice Department has paused implementation following a court order, raising doubts about the fund's future. President Donald Trump is reconsidering whether to move forward with a $1.8 billion...
Trump rethinking $2.5b fund amid corruption allegations, sources say
Trump rethinking $2.5b fund amid 'jaw-dropping' corruption allegations, sources say Wed 3 Jun 2026 at 4:49am US President Donald Trump is considering the future of a $US1.776 billion ($2.51 billion) fund for his political allies, sources say. His retreat is a nod to several legal setbacks and internal pushback the fund has encountered since it was announced two weeks ago. Here's what to know about the fund that sparked backlash from all sides of politics.
Trump halts $1.8bn ‘anti-weaponisation’ fund amid bipartisan backlash
Trump halts $1.8bn ‘anti-weaponisation’ fund amid bipartisan backlash The announcement comes after Trump met with congressional Republicans over concerns about his settlement with the IRS. United States President Donald Trump will reportedly drop his $1.8bn “anti-weaponisation” fund amid congressional backlash, including from fellow Republicans. On Monday, US media indicated the fund would be paused, though the White House has yet to publicly confirm the reports.
Trump admin backs off controversial $2B fund, clearing path for stalled GOP immigration bill
The Department of Justice (DOJ) pressed pause on the Trump administration's "anti-weaponization" fund on Monday, giving Senate Republicans runway to hammer through a massive immigration enforcement funding package in the process. The DOJ announced on X that it would abide by a Virginia federal court's order to not move forward with the fund. It comes as Republicans in the upper chamber punted their plan to advance a $72 billion immigration enforcement package over deep concerns about who...
Trump administration plans to drop DOJ's $1.8B 'lawfare' fund, reports say
The Trump administration plans to drop the Department of Justice's $1.8 billion "Anti-Weaponization Fund" in the face of legal and political pushback to it, reports said Monday. The fund was created as part of a settlement of President Donald Trump's $10 billion lawsuit against the Internal Revenue Service. It is intended to compensate people who were purportedly victims of prosecutorial overreach by the DOJ under the Biden administration.
Boys aged 11 and 12 airlifted out of state park after ‘roughhousing’ incident left one of them unconscious
Boys aged 11 and 12 airlifted out of state park after ‘roughhousing’ incident left one of them unconscious An adult chaperone started CPR on the unconscious boy while emergency crews responded to the scene - Bookmark - CommentsGo to comments Two Illinois boys were airflited out of Matthiessen State Park Friday after a “roughhousing” incident during a school field trip turned dangerous. Emergency crews responded to the park around 12:45 p.m. following a report that an adult chaperone began...
Dennis Quaid ditched LA for Nashville after the once 'fantastic' city went 'downhill'
Dennis Quaid is opening up about why he left Los Angeles, saying the once "fantastic" city has been on a downward slide for years. The 72-year-old actor joined the growing exodus of residents fleeing LA when he moved to Nashville, Tennessee with his wife Lauren Savoie, 33, in 2020.During an interview with Fox News Digital, "The Parent Trap" star, who lived in LA for decades, explained how he became frustrated and disillusioned with the management of the city, a sentiment that he believes is...