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Related Articles from SNS
Broadband amplification of organ of Corti vibrations in the mouse cochlear apex
Mammalian hearing depends on the active amplification of sound-evoked waves as they travel along the basilar membrane within the cochlea. This amplification is mediated by the outer hair cells (OHCs), which generate force to enhance the vibrations of the surrounding structures. While OHCs at a given location only amplify basilar membrane motion for a narrow frequency range, recent measurements show that the amplification of motions deeper within the organ of Corti is much more broadband.
Galectin and Myc enable cochlear progenitor expansion in vitro and in vivo
The neonatal cochlear epithelium harbors regenerative capacity, attributable to the transient greater epithelial ridge (GER). After injury, GER cells re-enter the cell cycle, migrate into the damaged organ of Corti, and differentiate into sensory or supporting cells in vivo; in culture, they proliferate to form inner ear organoids. The mechanisms underlying this competence remain unclear.