Cross-Linking Mass Spectrometry Data
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Methods for Inferring Interaction Potentials from Cross-Linking Mass Spectrometry Data
Announce Type: new Abstract: Cross-linking mass spectrometry (XL-MS) has emerged as a powerful quantitative technique for probing intra-protein structural information as well as protein-protein interactions at an unprecedented scale. XL-MS data yield information on the pairwise spatial proximity of proteins through inter-molecular linkers. However, systematic methods for adapting such data for coarse-grained interacting particle models remain limited.