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dCas allele sequestration (das-CRISPR): A Versatile New Method to Achieve Monoallelic Gene Editing in Mouse Embryos and in cell culture.
CRISPR-Cas9 technology is a powerful tool extensively used for genome editing in mouse and many other species. Streptococcus pyogenes Cas9 efficiently cuts both alleles in mouse zygotes leaving many edited embryos without a functional protein that might be needed to sustain development, to survive postnatally or to reproduce, thus complicating its overwhelmingly advantageous use in making gene modifications. About 25% of mouse genes are essential for embryonic development and another 7% are...
DAS-PINNs for high-dimensional partial differential equations: extending deep adaptive sampling to spacetime domains
Announce Type: new Abstract: Time-dependent high-dimensional partial differential equations (PDEs) with spatially localised and dynamically evolving solutions pose a fundamental challenge for physics-informed neural networks (PINNs), as uniform collocation sampling becomes increasingly ineffective in high-dimensional spatiotemporal domains. In this work, a deep adaptive sampling framework for PINNs is extended to the time-dependent setting by treating space and time as a unified domain...
Detection at the nanoscale: A phosphate-detecting electrochemical sensor
Detection at the nanoscale: A phosphate-detecting electrochemical sensor Sadie Harley Scientific Editor Andrew Zinin Lead Editor Graphene, the "wonder material," has shaped much of Suprem Das's research career. From nano-manufacturing to advanced printing for applications such as sensing and energy, Das is committed to finding graphene solutions with real-world impact. Das and his team manufacture graphene in the form of printable ink for various applications.
Watch: Mob thrashes and strips Dum Dum TMC councillor over ‘theft of relief material’
A mob on Friday stormed the house of North Dum Dum Trinamool Congress councillor Shankar Das and severely assaulted him, leaving him seriously injured. A video that quickly went viral purportedly shows a ‘kangaroo court’ stripping and beating him up. Local sources said Das was thrashed till Nimta police rescued him, following which he was admitted to a private hospital.
SagnacAssisted Enhanced OTDR for Distributed Acoustic Sensing: A Standardized Benchmark and Engineering Evaluation Framework
Announce Type: new Abstract: Phase-sensitive optical time-domain reflectometry ($\phi$-OTDR) is widely used in large-scale distributed acoustic sensing (DAS) because it provides distributed spatiotemporal monitoring over long sensing distances. Its field performance can still deteriorate because of polarization-induced fading (PIF), local signal degradation, and strong environmental interference. This study develops a Sagnac-assisted enhanced $\phi$-OTDR sensing architecture and a...
Drift-Augmented Scoring: Text-Derived Noise Robustness for Zero-Shot Audio-Language Classification
arXiv:2606.04844v1 Announce Type: new Abstract: Contrastive audio-language models such as CLAP enable zero-shot audio classification: a sound is labelled by matching its embedding to text prompt embeddings, with no labelled audio. This matching breaks down under acoustic noise, where accuracy and mAP fall by 12-30 percentage points at 0 dB SNR on standard benchmarks. We propose Drift Augmented Scoring (DAS), a small per-class bonus added to the cosine score.
How Mathura ashram became trap for women; ex-IITian sadhu held for sexual abuse
An IIT Roorkee graduate, who previously worked at a private company in Delhi NCR before moving to Mathura, Uttar Pradesh, to become a self-styled spiritual guru, has been arrested for allegedly luring young women into a spiritual group and sexually exploiting them under the pretext of performing religious and social rituals. Mathura (Rural) SP Suresh Chandra Rawat told TOI, “The accused, 30-year-old Abhishek Mishra, alias Adikarta Narayan Das, was arrested near Radha Kund in the Govardhan...
India’s Cockroach Party fights attempts to discredit the movement
India’s Cockroach Party fights attempts to discredit the movement To display this content from YouTube, you must enable advertisement tracking and audience measurement. Issued on: Modified: On this edition of Access Asia, we explore how India’s nascent Cockroach Janta Party has tapped into the frustrations of the country’s youth. We speak with the party’s spokesperson, Saurav Das, who tells us that the movement is demanding accountability from the government.
'In Pakistan, they used to stand with guns outside room': Litton on B'desh's T20 WC withdrawal
Four months after Bangladesh were removed from the 2026 T20 World Cup, the debate over who decided to skip the tournament refuses to die. While former interim sports advisor Asif Nazrul had claimed the players and the Bangladesh Cricket Board (BCB) jointly chose not to participate, captain Litton Das has once again rejected that version of events. The controversy began after Bangladesh raised safety concerns about playing in India amid regional tensions.
Elucidating the Control of Circular Dichroism in Ion Yield via Chirped Pulses with Purposeful Models
Announce Type: new Abstract: We theoretically investigate circular dichroism in the ion yield following $1+1+1$ ionization of 3-methylcyclopentanone using femtosecond linearly chirped laser pulses, inspired by recent experiments by Das et al. Phys. 27, 8043 (2025)]. To this end, we numerically solve the time-dependent Schr\"odinger equation and evaluate the total population in the Rydberg states at the end of the second absorption step.