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I-SAFE: Wasserstein Coherence Metrics for Structural Auditing of Scientific AI Models

Announce Type: replace Abstract: Deep learning models are increasingly used in scientific prediction tasks where strong benchmark performance is often interpreted as evidence of scientifically meaningful behavior. This interpretation is fragile, as models may exploit shortcut features, dataset-specific regularities, or distributional biases that are predictive on held-out data but not aligned with domain-relevant structure. To address this limitation, we introduce the \textsc{I-SAFE}...

arXiv CS 2d ago

SC-TauPath: A Structural Connectivity Attribution Framework for Mapping Tau Propagation Pathways in Alzheimer's Disease

arXiv:2606.04066v1 Announce Type: cross Abstract: Understanding how structural connections are associated with tau propagation in Alzheimer's disease (AD) remains a central open question, yet existing computational models either rely heavily on biophysical assumptions or lack neurobiologically interpretable pathway maps. We present SC-TauPath, a structural connectivity (SC) attribution framework that maps tau propagation pathways from in vivo neuroimaging data. SC-TauPath combines a Network...

arXiv CS 6d ago

Higher mortgage rates don't just keep buyers on the sidelines. Application denials rise too

Higher interest rates do more than just deter potential homebuyers — they may also block consumers from qualifying for a mortgage, according to new research. The rate of denials in loan applications was 15.1% in 2024, up from 12.2% in 2021, a rise that occurred alongside a surge in mortgage rates from below 3.5% to more than 6.5%, researchers at the Federal Reserve Bank of St. Louis said in a new blog post. At the same time, however, fewer consumers were applying for mortgages as rates...

CNBC 6d ago