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Quantifying the Localization of Histological Staining Markers within the GI Epithelial Unit Axis: A Gastrointestinal Spatial Pathology Plugin for ImageJ
Histological analysis is crucial for understanding gastrointestinal (GI) tract homeostasis and disease pathophysiology. Various histological stains are commonly used in research settings for assessing development, disease pathogenesis, and therapeutic impacts. Specifically in the ordered architecture of the GI epithelium, current semi-quantitative analysis of histological staining relies heavily on manual scoring rubrics and often lacks robust spatial assessment.
Sweet victory? Bengal BJP's GI tag push for Kansat, Mohan Bhog
The West Bengal BJP has begun preparations to secure Geographical Indication (GI) tags for several traditional sweets of the state that still lack recognition, aiming to promote them at national and international levels while also planning to set up 'Misthi Hubs' (Sweet Hubs) for organised production and export. A GI tag is a sign used on products that have a specific geographical origin and possess qualities or a reputation that are due to that origin. Geographical Indications are covered...
EGFR INHIBITION PROMOTES ENTEROENDOCRINE CELL DIFFERENTIATION CONTRIBUTING TO TREATMENT-ASSOCIATED DIARRHEA
Enteroendocrine cells (EECs) are specialized sensors of the gastrointestinal (GI) epithelium that regulate gut function and systemic metabolism through hormone secretion. The molecular pathways directing intestinal stem cell (ISC) differentiation into EECs are incompletely understood due, in part, to their rarity. We sought to identify novel regulators of human EEC differentiation using a high-throughput screen of FDA-approved drugs and human duodenal organoids.
Self-supervised Monocular Depth and Pose Estimation for Endoscopy with Latent Priors
Announce Type: replace Abstract: Accurate 3D mapping in endoscopy enables quantitative, holistic lesion characterization within the gastrointestinal (GI) tract, requiring reliable depth and pose estimation. However, endoscopy systems are monocular, and existing methods relying on synthetic datasets or complex models often lack generalizability in challenging endoscopic conditions. We propose a robust self-supervised monocular depth and pose estimation framework that incorporates a Generative...
After new drug’s ‘unprecedented’ results for pancreatic cancer, doctors look at other uses
Every single patient with advanced pancreatic cancer who walked into Dr. Zev Wainberg’s office told him they would rather take an experimental medication than endure another round of chemotherapy. Wainberg, co-director of UCLA Health’s GI Oncology Program, was leading a clinical trial of a new drug called daraxonrasib. All the study participants previously had chemotherapy that was starting to fail.
‘I’m carrying rage like a blood-filled egg’: the best of Glasgow International – review
From his deathbed photographs of his former lover to a face emerging from dirt, New Yorker David Wojnarowicz is the festival standout, although Renèe Helèna Browne’s film about cows contains multitudesSetting the mood for this year’s Glasgow International (GI) is a show dedicated to David Wojnarowicz – artist, writer and fixture of the 1980s East Village scene. Including paintings, photographs and video works, it is arranged inside a Georgian terrace house so decayed that you can see through...
‘I’m carrying rage like a blood-filled egg’: the best of Glasgow International – review
From his deathbed photographs of his former lover to a face emerging from dirt, New Yorker David Wojnarowicz is the festival standout, although Renèe Helèna Browne’s film about cows contains multitudesSetting the mood for this year’s Glasgow International (GI) is a show dedicated to David Wojnarowicz – artist, writer and fixture of the 1980s East Village scene. Including paintings, photographs and video works, it is arranged inside a Georgian terrace house so decayed that you can see through...
Channel Chart Location Privacy Based on Geo-Indistinguishability
Announce Type: new Abstract: Channel charting enables location-based services (LBSs) without requiring explicit position information by using pseudo-locations from the channel chart. While this property implies inherent privacy advantages, it does not provide formal privacy guarantees. In this work, we address location privacy in channel charting referred to as chart location indistinguishability (CLI), which extends geo-indistinguishability (GI) to channel charting representations.
Japanese manga fans urge Trump to stop using characters in his online posts
Renewed outrage at White House’s use manga and anime imagery after US president is depicted as ninja NarutoJapanese anime and manga fans are urging Donald Trump to stop using their favourite characters in his social media posts. About 20,000 people have signed a petition on Change.org entitled Protect Japanese Manga, protesting against the official White House X account posting videos featuring unauthorised use of imagery from the popular Dragon Ball, Yu-Gi-Oh! and Naruto series. Angry fans...
Protecting K-Nearest Neighbor Queries from Location Inference Attacks
Announce Type: new Abstract: The k-nearest neighbor query (kNNQ) is a core component of modern location-based services (LBS) and has been widely adopted in popular features such as ``people nearby''. However, its potential privacy risks have long been overlooked. In this work, we present the first two attacks against kNNQ, namely the geometric intersection location inference attack (GI-LIA) and the zero-order optimization location inference attack (ZO-LIA), revealing the inherent location...