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Gradient estimators for parameter inference in discrete stochastic kinetic models
arXiv:2604.02121v2 Announce Type: replace Abstract: Stochastic kinetic models are ubiquitous in physics, yet inferring their parameters from experimental data remains challenging. For deterministic models, parameter inference often relies on gradients, which can be obtained efficiently through automatic differentiation (AD). However, AD cannot be applied directly to the Gillespie stochastic simulation algorithm (SSA), since sampling from a discrete set of reactions introduces...
Gradient estimators for parameter inference in discrete stochastic kinetic models
Announce Type: replace-cross Abstract: Stochastic kinetic models are ubiquitous in physics, yet inferring their parameters from experimental data remains challenging. For deterministic models, parameter inference often relies on gradients, which can be obtained efficiently through automatic differentiation (AD). However, AD cannot be applied directly to the Gillespie stochastic simulation algorithm (SSA), since sampling from a discrete set of reactions introduces non-differentiable operations.
Team 'astonished' as rider kicked out of Giro d'Italia Women
Team 'astonished' as Lorena Wiebes kicked out of Giro d'Italia Women after winning stage one Sun 31 May 2026 at 1:23pm In short: Lorena Wiebes out-sprinted Elisa Balsamo and Lara Gillespie to win the opening stage of Giro d'Italia Women. The race jury found that Wiebes's bike was 200 grams underweight, leading to the Dutch champion being disqualified. Tomorrow's second stage will also likely finish in a bunch sprint, with Balsamo racing in the leader's pink jersey.
‘It’ll never be like that again’: Sonny Rollins and Steve Schapiro on jazz’s golden age – in pictures
Schapiro’s stunning images of jazz greats in New York – from Dizzy Gillespie to Elvin Jones – make up a new book featuring a foreword by late saxophone icon Rollins Continue reading...
‘It’ll never be like that again’: Sonny Rollins and Steve Schapiro on jazz’s golden age – in pictures
Schapiro’s stunning images of jazz greats in New York – from Dizzy Gillespie to Elvin Jones – make up a new book featuring a foreword by late saxophone icon Rollins Continue reading...
Miles Davis’s superior musical intelligence | Letters
Dr Richard Carter and Meirion Bowen respond to an editorial which argues that the musician still shapes modern music 100 years after his birthYour editorial marking the centenary of Miles Davis’s birth rather understates his musical intelligence (The Guardian view on 100 years after Miles Davis’s birth: why he still shapes modern music, 24 May). Unable to play with the facility of dazzling trumpeters like Dizzy Gillespie and Fats Navarro, it was less a case of his preferring “restraint and...
Arsenal’s party embodies the metropolitan swagger and angst of a divided city | Jonathan Liew
The crowd that gathered late into the night to celebrate on the streets reflected an idea of London where all are welcomeThe mounds of detritus pile up outside Finsbury Park station, like an offering to a vengeful deity. A deity gone rogue for the evening, demanding tribute specifically in the form of empty food cartons and abandoned Lime bikes. A deity that has finally decided to break the habit of 22 years.They approach via the familiar sidestreets, Gillespie Road, Benwell Road, Hornsey...
US confirms three new cases of flesh-eating screwworm in livestock
Department of Agriculture says new cases in Texas and New Mexico as officials move to combat parasite’s spreadThe US Department of Agriculture (USDA) on Monday confirmed three additional cases of New World screwworm – two more in Texas and the other in New Mexico, according to the agency’s animal health arm. The Animal and Plant Health Inspection Service said the two Texas cases affected a calf in La Salle county and a goat in Gillespie county.
Miles Davis’s superior musical intelligence | Letters
Dr Richard Carter and Meirion Bowen respond to an editorial which argues that the musician still shapes modern music 100 years after his birthYour editorial marking the centenary of Miles Davis’s birth rather understates his musical intelligence (The Guardian view on 100 years after Miles Davis’s birth: why he still shapes modern music, 24 May). Unable to play with the facility of dazzling trumpeters like Dizzy Gillespie and Fats Navarro, it was less a case of his preferring “restraint and...
Arsenal’s Premier League trophy parade: title celebrations in north London – live
⚽ Hundreds of thousands attend London event (2pm BST)⚽ PSG dash Arsenal’s Champions League dream | Mail JohnThis is the organised parade, what happened last Tuesday was far more impromptu. They approach via the familiar sidestreets, Gillespie Road, Benwell Road, Hornsey Road, the little shortcut past The Plimsoll pub.