Goldilocks
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Finding the Goldilocks zone: Modulating glycoprotein cleavage and fusogenicity optimizes the efficacy of a candidate Crimean-Congo hemorrhagic fever virus vaccine
Crimean-Congo hemorrhagic fever virus (CCHFV) is the etiologic agent of a lethal hemorrhagic disease spread by ticks throughout Europe, the Middle East, Africa and Asia. The lack of approved medical countermeasures and fundamental understanding of molecular mechanisms of viral assembly and egress have thus far curtailed disease prevention. Here, we identify and characterize key residues within the viral glycoprotein through forward and reverse genetics for vesicular stomatitis virus...
The Philosophy of the Out-of-Office Email
This is an edition of The Wonder Reader, a newsletter in which our editors recommend a set of stories to spark your curiosity and fill you with delight. Sign up here to get it every Saturday morning. For some people, an out-of-office message is a simple one-line email.
Giant fire tornadoes could clean up oil spills faster with less pollution
Giant fire tornadoes could clean up oil spills faster with less pollution What if one of the best ways to fight an oil spill is with a controlled fire tornado? - Date: - June 5, 2026 - Source: - Texas A&M University - Summary: - Researchers have shown that controlled fire whirls can clean up oil spills faster and more cleanly than traditional burning methods.
Why do Venus and Jupiter meet up in the sky so often? It's a symptom of a solar system that supports life on Earth
Why do Venus and Jupiter meet up in the sky so often? It's a symptom of a solar system that supports life on Earth "Orbital dynamics allows you to start to think about all those fun, different aspects of what makes our planet habitable, and ask how normal it is to have a habitable planet." Shortly after sunset on June 9, Venus and Jupiter will look very close together, in what is known as a planetary conjunction.
Digital Notebook Throwdown (2026): Kindle Scribe, ReMarkable Paper Pure
The final new Kindle Scribe, Amazon's e-reader that boasts digital notebook features and a larger screen, which was promised in 2025, has finally arrived. The Kindle Scribe Without Front Light ($430) was announced last year, but is available starting today. In the past, Amazon has launched a single version of the Kindle Scribe at a time.
This tiny Texas ranching town is now growing faster than anywhere in America
This tiny Texas ranching town is now growing faster than anywhere in America The South continues to dominate national growth patterns, claiming 10 of the country’s 15 fastest-growing cities and nearly all of the largest numeric population gains - Bookmark - CommentsGo to comments A former ranching community an hour north of Dallas has been named the fastest-growing city in the United States, leading a broader trend of families moving to outer suburbs as population growth slows in major...
Experts suspect state policy is putting some farmers in artificial drought
Farmer says flood plain harvesting has forced him to run cattle by the roadside Fri 5 Jun 2026 at 5:30am Paul Cameron watches his mob of thirsty cattle sink their heads into the Goan waterhole on the outskirts of Trangie in western New South Wales. Mr Cameron has driven his cattle to graze the scrubby patches of Crown land hugging the public billabong for more than a year. "I've been walking the stock to town … because we haven't got any water in our own system," Mr Cameron said.
Harry's and Coterie owner Mammoth Brands has ambitions to be the next CPG giant
Mammoth Brands wants to take on traditional consumer packaged goods companies, armed with a portfolio of disruptors in the personal and baby care categories that have won over consumers and retailers alike. For the last decade, upstarts like those owned by Mammoth have challenged the relevance and longstanding dominance of legacy giants like Procter & Gamble, Unilever and Kimberly-Clark. The trend has also played out across packaged food and beverage companies, like Poppi and Olipop taking...
How did Taiwan, Seoul overtake India? Drop from 5th to 7th largest stock market - explained
In a span of just over a week, the Indian stock market has gone from being the world’s fifth largest to the seventh largest by market capitalization. First overtaken by Taiwan last week, India has now dropped below South Korea as artificial intelligence-driven rallies in these stock markets propel them to fresh highs. But the fall to seventh rank is not just about the rallies in South Korea and Taiwan.
A Kinetic Energy Perspective of Flow Matching
arXiv:2602.07928v2 Announce Type: replace Abstract: Flow-based generative models can be viewed through a physics lens: sampling transports a particle from noise to data by integrating a learned velocity field, and each sample corresponds to a trajectory with its own dynamical effort. Motivated by classical mechanics, we introduce Kinetic Path Energy (KPE), an action-like, per-sample diagnostic that measures the accumulated kinetic effort along an ordinary differential equation (ODE)...