Grade 2 to Grade 3
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A thalamus–brainstem attractor network drives history-biased decisions
Abstract Natural environments often change gradually, making it adaptive to bias decisions on the basis of the recent past — a phenomenon known as serial dependence1,2,3. Large-scale recordings during behaviour have identified that serial dependence is a common motif for decision-making, with neural representations of past experiences found throughout the brain4,5,6,7,8,9,10,11. However, it remains unclear whether this bias arises from dedicated neural circuits with history-specific...
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.
Interpreting Learning Under Competing Models: Joint and Stepwise Approaches for Dynamic Cognitive Diagnosis
Announce Type: new Abstract: Digital learning environments record learners' responses to individual items, making it possible to study the development of specific skills rather than overall scores. Drawing conclusions about learning from these data requires a model that links responses to latent skills and tracks how mastery changes over time. When the skills measured by each item are unknown, the analyst must decide whether to estimate this structure, the Q-matrix, jointly with the learning...
Ahoy, DECmate II the little PDP-8 that could
Now, that's a lot of word processing. But under the hood it's still at least PDP-8 adjacent, even considering its oddities and incompatibilities, and you can make it do many of the things a full-size Eight can. We'll take this basic unit, convert the floppy drives to solid state, tap the video output, and put it through its paces.
A machine-learning-assisted progressive digit-randomness screening framework for detecting non-random patterns in raw numerical research data
Announce Type: new Abstract: Raw numerical datasets remain less systematically examined in integrity screening than images, plagiarism, or summary-statistic inconsistencies. We developed the Fabrication-risk Digit Randomness Screening model (FDRS), a statistical and machine-learning framework for detecting non-random digit-pattern irregularities in numerical research data. FDRS integrates single- and joint-decimal-digit tests, Cramer's V, entropy metrics, Kullback-Leibler divergence,...
Belmont Stakes 2026 at Saratoga Race Course: Best bets, exotics, 'Pick 5' for the Grade 1 stakes races
This will be the final of three consecutive years that the Belmont Stakes will run at the mecca of horse racing: the Saratoga Race Course. Traditionally held at Belmont Park, the third jewel of horse racing’s Triple Crown has been held in Saratoga during Belmont's renovations and will return to its original home next year. As you probably already know, we won’t get a Triple Crown winner.
Is Australia sucking the joy out of childhood?
Some countries are protecting a child's right to play — not Australia Wed 10 Jun 2026 at 5:11am The first time Renae Powell waved her eldest child through the primary school gates, she felt something was wrong. Because of teacher supervision requirements, play was outlawed before and after school.
Parent 'thought it was a joke' upon hearing year 3 NAPLAN tests stolen
Year 3 NAPLAN tests stolen from FedEx van in Melbourne Tue 2 Jun 2026 at 5:11am In short: NAPLAN tests of about 70 primary school students from Melbourne's inner-north are missing after a the van carrying them was stolen on the way to exam markers on April 1. The tests contained the names, dates of birth, year levels and schools of the students. Victoria Police is still investigating the theft and there have been no arrests.
Grading bold preseason predictions for all 30 NBA ...
Before this NBA season began, I made 30 bold but realistic predictions, one for each team. In retrospect, some of them made me look prescient and smart. So as the 2025-26 season winds down and the offseason approaches, it's a good time to reflect on those scattered prognoses.
CS336: Language Modeling from Scratch
Course Staff Logistics - Lectures: Monday/Wednesday 3:00-4:20pm in Skilling Auditorium - Recordings: YouTube playlist - Office hours: - Percy Liang: Fridays 11am-12pm in Gates 366 - Tatsu Hashimoto: Tuesdays 11-12am in Gates 364 - Marcel Rød: Tuesdays 4:30-5:30pm in Gates 498, Wednesdays 4:30-5:30pm in Gates 415 - Herman Brunborg: Wednesdays 1:30-2:30pm, Fridays 1:30-2:30pm, location Gates 392 - Steven Cao: Mondays 4:30-5:30pm, Thursdays 9:30-10:30am, Gates 200 - Contact: Students should ask...