HSV
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Related Articles from SNS
Differential Sensitivity of HSV-1 and PRV to IFN-{lambda} Reveals a Neuron-Specific Antiviral Role for RSAD2
Alpha herpesviruses (-HV) initially infect mucosal epithelial cells and subsequently establish lifelong latency in the peripheral nervous system (PNS). Herpes simplex virus-1 (HSV-1), a human pathogen persisting in the majority of the adult population, shares neuroinvasive properties with Pseudorabies virus (PRV), a swine -HV, commonly used as a model -HV. Utilizing primary peripheral neuronal cultures, we previously showed that IFN-{lambda} pre-treatment significantly reduced PRV yield.
Semimage: HSV-Based Semantic Image Encoding for Disentangled Text Representation
arXiv:2512.00088v2 Announce Type: replace Abstract: We propose SemImage, a novel method for representing a text document as a two-dimensional semantic image to be processed by convolutional neural networks (CNNs). In a SemImage, each word is represented as a pixel in a 2D image: rows correspond to sentences and an additional boundary row is inserted between sentences to mark semantic transitions. Each pixel is not a typical RGB value but a vector in a disentangled HSV color space, encoding...
Viral Nuclease Inhibitors: Small molecule disruptors of the UL12 alkaline nuclease display broad anti-herpes virus activity
Herpes simplex virus-1 (HSV-1) UL12 gene encodes a well-conserved 5' [->] 3' alkaline exonuclease. UL12 collaborates with the HSV single-strand DNA binding protein ICP8 to mediate recombination-dependent replication of viral DNA and is essential for the production of DNA that can be packaged into infectious virus.