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Fluorescent nanosensor detects key gut biomarker in minutes for faster testing
Fluorescent nanosensor detects key gut biomarker in minutes for faster testing Sadie Harley Scientific Editor Robert Egan Associate Editor A research collaboration has developed a novel fluorescent nanosensor capable of rapidly detecting indole-3-propionic acid (IPA), an emerging biomarker linked to gut health and disease. The breakthrough is described in the team's paper, "Fluorescent Nanosensor for Indole-3-Propionic Acid Detection in Gut Health Monitoring," published in the journal...
‘Sexy as hell’: filthy and hilarious Heated Rivalry parody musical comes to New York
The smutty hockey show gets the Off-Broadway treatment with shirtless scenes, hilarious one-liners and a Liza Minnelli send-upWalking into the Culture Club in West Chelsea, New York, for a performance of Heated Rivalry: The Unauthorized Musical Parody last week, I was met by three ghosts left over from when the space was called the McKittrick hotel and it hosted the immersive spookfest, Sleep No More. The first was the phantom of clever detail: cans of Athletic IPAs for sale, a cute,...
VelocityFM: Short-Horizon Protein Trajectory Prediction via Flow Matching in Velocity Space
Protein dynamics is fundamentally a trajectory prediction problem, but molecular dynamics (MD) simulation remains expensive and static structure predictors do not model time-ordered motion. We present VelocityFM, a short-horizon protein trajectory predictor that applies rectified flow matching in velocity space over residue frames and torsions. The model combines six Invariant Point Attention (IPA) blocks with a two-layer per-residue temporal self-attention encoder, and is trained on 710...
Greene King giving away free pints this World Cup - how to claim yours
Greene King giving away free pints this World Cup - how to claim yours The free drinks will be available at select Greene King, Flaming Grill, Hungry Horse and Belhaven pubs on June 11 when Mexico takes on South Africa A major UK pub chain is giving away free pints to celebrate the start of the World Cup. The free drinks will be available at select Greene King, Flaming Grill, Hungry Horse and Belhaven pubs on June 11, when Mexico takes on South Africa in the tournament’s opening match.
The intracies of modern camera lens repair (2024)
Sigma 45mm f/2.8 Lens Repair & Analysis [05.12.24] I have a camera gear collection problem and as part of my personal 12 step plan, I restrict myself from purchasing functioning lenses. This sounds illogical, and it frankly is, but it's very hard for me to resist heavily discounted lenses.
Hyaluronic Acid Plays Differential Molecular Weight and Concentration Dependent Pathway Centric Changes to Human Lung Derived Microvascular Endothelial Cells in Culture
Background Hyaluronan (HA) is a major extracellular matrix glycosaminoglycan that regulates vascular integrity and immune signaling in the lung. Its biological effects are strongly size-dependent, with high-molecular-weight HA (HMW-HA) generally protective and low-molecular-weight HA (LMW-HA) pro-inflammatory. However, how different HA sizes and concentrations globally remodel endothelial cell signaling remains poorly understood.
NYC cancels Knicks NBA Finals watch party over Trump visit as MSG fires back
The Knicks are two wins away from a championship, MSG is preparing for its biggest game in three decades and New York City just canceled the party. As the Knicks prepare to host the San Antonio Spurs for Game 3 of the NBA Finals on Monday night with a 2-0 series lead, thousands of ticketless fans hoping to pack the Plaza33 outdoor watch party just learned there will be no party at all. The NYPD claims the party is off due to security for President Donald Trump's visit and its massive Secret...
UK's struggling pubs pin their hopes on England reaching World Cup final with £275m in beer up for grabs
UK's struggling pubs pin their hopes on England reaching World Cup final with £275m in beer up for grabs Pub bosses say England's World Cup team could deliver "huge good mood boost" to the nation as pubs are set to serve a bumper 55 million extra pints - if England make it to the World Cup finalthat is Thomas Tuchel’s England team is set to prove a World Cup winner for the nation’s pubs. After all the build-up, the footballing phenomenon finally kicks off on Thursday - and fans are hoping...
Signal says UK plan to scan devices for nude images 'endangers us all'
Signal insists that plans to compel tech companies to scan devices for nude images of children announced by UK Prime Minister Keir Starmer on Monday at London Tech Week "will not keep children safe." "It endangers us all," the encrypted messaging platform said, adding that the mechanism required to implement it would be "dangerous." And it wouldn't be a pro-privacy statement without calling it "dystopian."