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Applying Spatial Statistics to Spatial Transcriptomics Reveals Local Association Between M2-like Macrophages and Fibrosis in Diabetic Kidney Disease
Renal fibrosis is the common final pathway of chronic kidney disease (CKD), driven in part by myofibroblast-mediated extracellular matrix deposition. M2 macrophages have been implicated as a source of myofibroblasts through macrophage-to-myofibroblast transition (MMT), yet whether M2 macrophages are pro- or anti-fibrotic remains controversial, and the spatial context in which MAC-M2-fibrosis coupling occurs is unknown. Here, we applied geographically weighted regression (GWR), a spatial...
Millions warned after Waitrose dessert labelling mistake
Millions warned after Waitrose dessert labelling mistake A recall notice has been issued by the Food Standards Agency Waitrose is recalling a dessert which has undeclared ingredients that could prove dangerous for some people. Waitrose & Partners are recalling packs of 4 Richly Fruited Hot Cross Buns because the product contains barley which is not declared on the label. The recall covers any pack with a best-before date of June 6.