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Author Correction: Physiology and immunology of a pig-to-human decedent kidney xenotransplant
Nature, Published online: 04 June 2026; doi:10.1038/s41586-026-10694-2Author Correction: Physiology and immunology of a pig-to-human decedent kidney xenotransplant
Cancer’s favorite escape trick may actually make it easier to kill
Cancer’s favorite escape trick may actually make it easier to kill - Date: - June 4, 2026 - Source: - Baylor College of Medicine - Summary: - Scientists have uncovered a surprising new way the immune system fights cancer, overturning a core belief that has guided immunology for decades. The research found that when cancer cells shut down a key immune-recognition molecule called MHC I—a common trick used to hide from “killer” T cells—they can actually become more vulnerable to attack by a...
Altered Tonsillar Microbiome in Children with Down Syndrome and Obstructive Sleep Apnea
Background and Objectives: Children with Down syndrome (DS) have a high prevalence of obstructive sleep apnea (OSA) due to anatomic, neuromuscular, immunological and metabolic factors, yet the contribution of the tonsillar microbiome to airway obstruction in this population remains unexplored. We hypothesized that DS-associated OSA would be associated with a distinct tonsillar microbiome compared to non DS OSA. Methods: Tonsillar tissue from 22 DS and 18 NDS participants were analyzed by 16S...
Intratumoral B7H3:CD3 Bispecific T-cell Engager Drives Localized T-cell Accumulation in Canine Sarcoma Patients
Background: Bispecific T-cell Engagers (TCEs) targeting B7H3 (CD276) show promise for solid tumors but are limited by systemic toxicities and poor tumor penetration. Intratumoral (IT) delivery is proposed as a solution, but the safety and spatial pharmacodynamics (PD) remain poorly defined in these malignancies. Spontaneous canine tumors serve as a highly translatable model for human therapeutic development due to its clinical, genetic, and immunological similarities to human patients.
Preserved CD4+ T cell helper function and coordinated antiviral immunity in people with HBV/HIV co-infection on long-term therapy
ABSTRACT Background & Aims: People with HBV/HIV co-infection on antiretroviral therapy achieve higher rates of HBV functional cure than those with HBV mono-infection, yet the immunological basis remains poorly characterised. HBV-specific CD4+ T cell responses are critical for viral control and functional cure but have been scarcely examined in HBV/HIV co-infection. Our previous studies in HBV/HIV co-infection demonstrated preserved stem-like CD8+ T cells and NK cell functional responses, but...
Immunomodulatory Effects of Insulin-Derived Fibrils from Infusion Pumps: Role of Phenolic Preservatives in Macrophage Activation
Background: Protein fibrillation represents a critical challenge in therapeutic insulin delivery, yet the structural determinants and immunological consequences of insulin-derived fibrils (IDFs) formed in the presence of phenolic preservatives remain poorly characterized. This study investigated the structural characteristics of IDFs formed with (IDF (+)) and without (IDF (-)) phenolic preservatives and elucidated their differential immunomodulatory mechanisms in bone marrow-derived...
The secret to pigeons’ incredible navigation was hiding in their liver
The secret to pigeons’ incredible navigation was hiding in their liver Pigeons may owe their remarkable homing ability not to their brains or eyes, but to magnetic-sensing immune cells hidden in their livers. - Date: - May 31, 2026 - Source: - Max Planck Institute of Animal Behavior - Summary: - Scientists have uncovered a surprising navigation system in pigeons: iron-filled immune cells in the liver that may act like tiny magnetic sensors. Birds deprived of these cells struggled to find...
Q&A: Most biology education guidelines lack any connection to society, researchers explain why that's a problem
Q&A: Most biology education guidelines lack any connection to society, researchers explain why that's a problem Sadie Harley Scientific Editor Andrew Zinin Lead Editor Is it a doctor's job to get the best outcomes for their patients or to tell the truth? What happens when these two things are not aligned? These are questions that University of Washington students have to wrangle with in Biol 180: Introductory Biology.
Smoke engulfed their cities. Did it make their children sick?
Mothers fear children's chronic illnesses are linked to bushfire smoke during pregnancy Sun 31 May 2026 at 5:16am Six years after Black Summer bushfires, parents and doctors face an unsettling question: What does bushfire smoke do to babies in the womb? This story is a collaboration between the ABC's climate team and climate media organisation Grist. They never thought the fires would reach them.
Rare type of Lyme disease found for the first time in New York
There’s a new type of Lyme disease in New York state. Almost all cases of the tick-borne illness in the United States are caused by corkscrew-shaped bacteria called Borrelia burgdorferi. But B. burgdorferi is actually one of two Lyme disease-causing species in the U.S.