Inputs and Ensemble Formation Dendritic spines

Connectivity Logic of Dendritic Spines in Cortex: Increased Inputs and Ensemble Formation

Dendritic spines, small protrusions covering the dendrites of most neurons, are fundamental elements of synaptic connectivity, yet their network-level organization remains poorly understood. Here we leverage the large-scale MICrONS volumetric electron microscopy dataset of mouse primary visual cortex to explore the connectivity logic of dendritic spines across multiple spatial scales. Our analysis provides structural support for the ``connectivity and diversity'' hypothesis, showing that,...