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Pushing the Limits: A Framework to Reform Institutional Ethics Review of Environmentally-Impactful Computing Research
new Abstract: Computationally-intensive research (CIR) takes place on a wide variety of topics including AI. Its environmental impact is potentially significant yet it does not always fall clearly within the scope of organisational ethics review policy on its own merits. Many academic institutions have ethics oversight bodies (e.g. Research Ethics Committees or Institutional Review Boards) that occupy a potentially powerful position to encourage recognition of these issues and seek reflexive...
A prognostic human brain network for diffuse midline glioma
Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.
The Painful Truth About Long Covid
Nothing about long Covid adds up. Consider prevalence rates: How could one study find it affected 3.3 percent of the population of the UK but others an alarming 51 percent of South Americans and 86 percent of Egyptians? Or treatment methods: The BMJ’s systematic review of ways to treat long Covid lists two as supported by moderate evidence, cognitive behavioral therapy and physical exercise.
The Congresswoman Who Got Trump’s Name Off the Kennedy Center
Three months ago, a 75-year-old lawmaker filed a complaint as part of an ongoing lawsuit in federal court, claiming that she had been unlawfully excluded from an upcoming board meeting that would determine the fate of the John F. Kennedy Center for the Performing Arts. It turned out that the invitation had landed in her spam folder—an admission that quickly became a political punch line, a real-life Veep episode in Washington politics. Today, the plaintiff—Representative Joyce Beatty—feels...
Whole-genome duplication shaped cell-type evolution in the vertebrate brain
Abstract The complex brains of vertebrates have more cell types than those of their closest relatives. Whole-genome duplications (WGDs) occurred during early vertebrate evolution1, but it is unclear whether the duplicated genes (ohnologues) facilitated cell-type evolution. Here using brain single-cell transcriptomes from five chordates—human2, mouse3, lizard4, lamprey5 and amphioxus—we report that many cell-type families with conserved core transcription factors in vertebrates do not show...
Trump says judge who ruled against him on Kennedy Center ‘should be brought up on charges’
Trump says judge who ruled against him on Kennedy Center ‘should be brought up on charges’ Trump accused the judge of ruling against him ‘because his wife probably told him to do so’ and went on to accuse him of having a conflict of interest because of his wife's politics - Bookmark - CommentsGo to comments President Donald Trump is calling for a federal judge who ruled against his Kennedy Center renaming and renovation plans to face charges. On Saturday, Trump issued a more than 700-word...
When drug discovery fails: scientists share their frustrations with the process
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What Trump’s New Plan for the 250th Reveals
This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. What’s a party without a little music? This year, the National Mall was meant to host a free summer concert series in celebration of the 250th anniversary of our nation’s founding.
Trump’s ‘disparaging’ ban on trans troops is unconstitutional, appeals court rules
Trump’s ‘disparaging’ ban on trans troops is unconstitutional, appeals court rules Judge says the administration’s policy was ‘driven by the bare desire to harm a politically unpopular group’ - Bookmark - CommentsGo to comments A divided federal appeals court in Washington, D.C. has blocked Donald Trump’s administration from removing transgender service members from the U.S. military, a major victory for trans troops who have been subjected to “demeaning” and “disparaging” orders from the...
The Betrayal of Black Patriots
Photographs by Nate Langston PalmerDaniel “Chappie” James Jr. became commander of the Wheelus Air Base, near Tripoli, just after rebels under Muammar Qaddafi took control of Libya in a coup in 1969. In the midst of the insurgency, Qaddafi led an effort to break into the U.S. air base, but James managed to close the gate in time to prevent the young rebel from entering. The incident, which James recounted in a 1978 interview, would come to be the stuff of Air Force lore.