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Expedition to Antarctica advances research on potential melanoma treatment
Expedition to Antarctica advances research on potential melanoma treatment Lisa Lock Scientific Editor Andrew Zinin Lead Editor Deep beneath the icy waters surrounding Antarctica, a small marine organism may hold clues to a future cancer treatment. Researchers from USF recently returned from a six-week expedition in one of the most remote environments on Earth to study a species of ascidian, or sea squirt, that contains a bacterium capable of killing melanoma cancer cells. The discovery was...
A prognostic human brain network for diffuse midline glioma
Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.
A single protein may be holding back CAR T cancer therapy
A single protein may be holding back CAR T cancer therapy - Date: - June 2, 2026 - Source: - University Hospital Tübingen - Summary: - A newly identified protein may be one of the biggest obstacles holding CAR T-cell therapy back. Researchers found that NFIL3 causes these engineered immune cells to become exhausted and lose their cancer-fighting power over time. When NFIL3 was disabled, the cells remained stronger for longer and controlled tumors more effectively in animal models.
Republicans are trying to kill science in this country
Researchers say the Trump administration is finding new ways to punish science Standing in his laboratory, Harvard professor Sean Eddy gazes at a row of vacant work stations. More than a year ago, this lab was filled with over a dozen researchers. On a given day they might be working independently on analyzing genomic sequencing or gathered around the group table, drinking coffee and helping each other troubleshoot questions about genomic data from different species.
Common plastics soak up ballistic impacts thanks to a cross-linking molecule
Common plastics soak up ballistic impacts thanks to a cross-linking molecule Sadie Harley Scientific Editor Robert Egan Associate Editor With help from a novel cross-linking molecule, MIT chemists have shown they can substantially improve the ballistic impact resistance of common polymers, including polystyrene and a type of rubber used to make shoe soles. Polystyrene is a hard, glassy polymer that is used to make many types of plastic containers, such as bottles and mugs, as well as...
Cancer survivors may see surprising benefits from one specific exercise, study says
For many, surviving cancer comes with an automatic new lease on life but other survivors continue to experience physical and emotional challenges long after treatment ends. Yoga may significantly reduce the insomnia, fatigue and mood disturbances many survivors endure after remission, a recent clinical trial found. Mood disturbance and insomnia are "two of the most pervasive and troubling side effects experienced by cancer survivors for years after completing adjuvant treatments," the...
Do turmeric and curcumin have any actual health benefits?
As the temperature drops in Australia, I’ve been seeing recipes on social media for “golden milk”, a mix of turmeric, other spices and honey in warm milk. In addition to being delicious, it is meant to have medicinal qualities, thanks to a compound in turmeric called curcumin, which gives it its distinct yellow colour. Curcumin is said to have anti-inflammatory properties that are protective against cancer, arthritis, hay fever, Alzheimer’s disease, menopause symptoms and many other ailments.
SIRT7 regulates dosage compensation and safeguards the female X chromosome
Abstract Sirtuins are deacetylases implicated in stress responses and longevity in mammals1,2. Although their differential impact on disease for the two sexes has been noted3,4,5,6,7, the underlying reasons are unclear. Here, using Sirt7 as a model in mice, we examine the mechanisms leading to sex differences and find that Sirt7−/− female mice have decreased fitness throughout their lifespan.
Firefighters face a higher risk of skin cancer, but nano fabrics with tiny, rough fibers can help keep them safer
Firefighters face a higher risk of skin cancer, but nano fabrics with tiny, rough fibers can help keep them safer Lisa Lock Scientific Editor Andrew Zinin Lead Editor Wildland firefighters are exposed to a mix of harmful chemicals in the smoke they breathe and the ash and soot that gets on their clothing. Over long assignments fighting fires that can last for days to weeks, those chemicals can be absorbed by their skin. Some of those chemicals are carcinogens.
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.