Investigating Energy Bounds
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Investigating Energy Bounds of Analog Compute-in-Memory with Local Normalization
arXiv:2602.08081v2 Announce Type: replace Abstract: Modern edge AI workloads demand maximum energy efficiency, motivating the pursuit of analog Compute-in-Memory (CIM) architectures. Simultaneously, the popularity of Large-Language-Models (LLMs) drives the adoption of low-bit floating-point formats which prioritize dynamic range. However, the conventional direct-accumulation CIM accommodates floating-points by normalizing them to a shared widened fixed-point scale.
Online Span Minimization for Flexible Uniform Jobs
arXiv:2606.06681v1 Announce Type: new Abstract: Motivated by the critical need for energy-efficient scheduling in cloud computing, this paper investigates Span Minimization, a fundamental variant of the well-studied BusyTime problem. In the general BusyTime problem, $n$ jobs characterized by release times, deadlines, and processing times must be partitioned into bundles of capacity $B$, where the objective is to minimize the total active duration of the virtual machines. Span minimization...
The Last Evolution, by John W Campbell Jr. (1932)
The Project Gutenberg EBook of The Last Evolution, by John Wood Campbell This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Project Gutenberg License included with this eBook or online at www.gutenberg.org
Glittering star cluster image reveals missing patch of stars: 'We were not looking for the gap, but we found it'
Glittering star cluster image reveals missing patch of stars: 'We were not looking for the gap, but we found it' The new view captures an irregularity in how stars are distributed within NGC 6397. A gorgeous new portrait of an ancient star cluster reveals an unexpected imperfection: a visible gap in the brightness of its stars. The stunning image, taken by the European Space Agency’s (ESA) Euclid space telescope, captures NGC 6397 — one of the closest globular clusters to Earth.
When AI Builds Itself: Our progress toward recursive self-improvement
For most of AI’s history, humans drove every step in its development cycle. But at Anthropic, we are delegating a growing share of AI development to AI systems themselves, which is speeding up our work. Taken far enough, and given enough compute, that trend points to an AI system capable of fully autonomously designing and developing its own successor.
Light-induced quantum friction of carbon nanotubes in water
Abstract Friction slows down moving objects at both macroscopic and microscopic scales1. At the electronic level, quantum friction describes direct transfer of momentum between a liquid and the electrons of a solid2. Owing to its microscopic nature, this phenomenon remains experimentally challenging to capture3.
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.
CEO of tech company arrested for supplying US-origin computer parts to Iran: How California resident negotiated, purchased and arranged shipment of large quantities of 'banned' US technology for over 10 years
Jamshid Ghomi, a dual US-Iranian national and CEO of an Iran-based technology company has been arrested today on a federal criminal complaint. As per a press release filed by U.S. Attorney's Office, Central District of California, Ghomi is accused of violating US sanctions against Iran by shipping sophisticated US-origin networking, security, and encryption equipment for Iranian customers — including the Iranian regime’s nuclear and military establishment. Ghomi, 33, is a resident of Newport...
Diverse binding poses of agonistic neurotoxins on human Na<sub>v</sub>1.6
Abstract Voltage-gated sodium (Nav) channels are key targets of various venomous toxins. Deciphering the binding poses and mechanisms of action of representative toxins will help to dissect the functional mechanism of the channels and facilitate therapeutic development targeting Nav channels1,2. Here we present cryo-electron microscopy (cryo-EM) structures of distinct binding poses of three agonistic peptide toxins on the human Nav1.6–β1 channel complex.
Republicans vs. the Fourteenth Amendment
Subscribe here: Apple Podcasts | Spotify | YouTubeIn this episode of The David Frum Show, The Atlantic’s David Frum opens with his thoughts on the Brexit vote, which was cast 10 years ago this month. David explains why Brexit has not only been a failure but has led to years of political instability in the U.K. in the decade following the British vote to leave the European Union. Then, David is joined by Professor David W. Blight to discuss the blood-soaked aftermath of the Civil War and the...