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Dependencies and Dataflow in Seed-Filter-Extend Pipelines
Announce Type: new Abstract: Comparing genomes is critical for discovering mutations, tracking evolutionary lineages, and advancing cross-species genomics. Fundamentally, this reduces to an O(n^2) string-matching dynamic programming (DP) problem, a challenge that has driven decades of performance research. However, executing a strict O(n^2) DP algorithm is computationally intractable for genomes spanning millions to billions of base pairs.