Life Biosciences
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Longevity Startup Doses First Human in Bid to Reverse Age-Related Sight Loss
A longevity startup has dosed its first patient with a drug to reverse age-related sight loss. Life Biosciences is testing its ER-100 drug, which has been shown to restore vision in monkeys, for safety and side effects in a study of around 18 adults over the next year. It will be targeting patients with glaucoma and NAION, two conditions causing damage to crucial cells in the optic nerve, which transmits visual information from the back of the eye to the brain.
This new diabetes pill burns fat without the downsides of Ozempic
This new diabetes pill burns fat without the downsides of Ozempic - Date: - June 3, 2026 - Source: - Karolinska Institutet - Summary: - Scientists have developed an experimental diabetes and obesity pill that works in a completely different way from drugs like Ozempic. Rather than reducing hunger, it activates metabolism in skeletal muscle, helping lower blood sugar and increase fat burning while preserving muscle mass. Early clinical results suggest the treatment is safe and well tolerated.
Some drugs 'fail' because of unrealistic testing conditions, scientists discover
Some drugs 'fail' because of unrealistic testing conditions, scientists discover Sadie Harley Scientific Editor Robert Egan Associate Editor A drug once dismissed as ineffective suddenly worked—when scientists tested it under more realistic conditions that mimic the human body. In this surprising new discovery, Northwestern University scientists uncovered a hidden rule of drug behavior. A medicine's effectiveness can change dramatically depending on the conditions inside our cells.
New 3D microscope technology captures high-resolution tissue images at a fraction of the cost
New 3D microscope technology captures high-resolution tissue images at a fraction of the cost Sadie Harley Scientific Editor Robert Egan Associate Editor A team led by Raju Tomer, professor of biological sciences at Columbia University, has created a new design for microscopes and microscope lenses that could push 3D tissue imaging beyond state-of-the-art systems while drastically cutting costs and complexity. Details of the design were published in the journal Nature Biotechnology. Modern...
A chromosome from a frozen rat has been resurrected inside mice
The de-extinction company Colossal Biosciences could be about to get leapfrogged. It might be possible to resurrect mammoth chromosomes in living cells after scientists transferred a chromosome from a rat that has been deep-frozen for more than a year into living mouse cells. They then generated entire mice in which some of their cells contain an added rat chromosome.
Infrastructure for African mines destroying forests at 34 times the rate of the mines themselves
Infrastructure for African mines destroying forests at 34 times the rate of the mines themselves Gaby Clark Scientific Editor Robert Egan Associate Editor Industrial-scale mining in Africa to support global supply chains is leading to unprecedented deforestation across the continent, with 34 hectares of forest removed for every single hectare of active mine site. The scale of mining's deforestation footprint is laid bare in a new University of Sheffield-led study showing that, between 2001...