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Label-Conditioned Cross-Modal Fusion for Adult-to-Pediatric ECG Transfer via Curriculum-Gated Contrastive Alignment

Announce Type: replace Abstract: Automated pediatric electrocardiogram (ECG) interpretation remains challenging because developmental differences in heart rate, intervals, and waveforms limit the transferability of models trained mainly on adult data, while expert-labeled pediatric ECG cohorts are scarce. We propose PEACE (Pediatric-Adult ECG Alignment via Cross-modal Enhancement), an adult-to-pediatric ECG transfer framework pretrained on MIMIC-IV ECGs and adapted to pediatric targets....

arXiv CS 1d ago

SafeRx-Agent: A Knowledge-Grounded Multi-Agent Framework for Safe and Explainable Medication Recommendation

arXiv:2605.29146v2 Announce Type: replace Abstract: Medication recommendation predicts medications for patient visits, but existing methods still face two key challenges. At the model level, traditional drug recommendation methods only predict structured drug codes with limited evidence grounding, while LLM agents can use richer clinical context but may lack safety verification and traceability. At the task level, existing benchmarks often use broad medication categories, which ignore...

arXiv CS 9d ago

HoT-SSM:Higher-order Temporal Knowledge Graph Reasoning with State Space Models for Health Care

Announce Type: new Abstract: Medical knowledge graphs (MKGs) infused with clinical knowledge have been increasingly used to model electronic health records (EHRs) to support interpretable predictions in healthcare domain. However, existing MKG-based approaches are limited in capturing pairwise relations between clinical concepts (e.g., conditions, procedures, and medications), and restricts their ability to model higher-order interactions among co-occurring or semantically related concepts....

arXiv CS 5d ago

DEM: A Distilled Explanation Model for Interpretable Anomaly Detection in Physiological Sensor Networks

arXiv:2605.31007v1 Announce Type: new Abstract: Anomaly detection in physiological sensor data from Wireless Body Area Networks (WBANs) can be caused by sensor faults, network disruptions, or missing data, leading to false alarms. Hence, it demands both high predictive accuracy and clinically interpretable explanations. Existing approaches rely either on black-box models that achieve strong performance but offer no transparency, or on post-prediction explanation methods such as SHAP and LIME.

arXiv CS 9d ago

TRACE: A Temporal Conditional Estimation for Multimodal Time Series Foundation Models

arXiv:2606.06285v1 Announce Type: new Abstract: Time series foundation models (TS-FMs) aim to learn generalizable temporal representations that can be adapted to a wide range of downstream tasks. In real-world multimodal settings, time series are frequently affected by temporal misalignment and partial modality missingness, where different modalities are observed at heterogeneous time scales or are partially absent. Existing approaches typically rely on naive imputation or masking...

arXiv CS 5d ago

Med-HEAL: Analyzing and Mitigating Hallucinations in Medical LLMs with Hallucination-Aware In-Context Learning

arXiv:2606.01301v1 Announce Type: new Abstract: Hallucinations in medical large language models (LLMs) pose serious risks for clinical decision support, particularly when models must reason over complex electronic health records (EHRs). However, existing benchmarks often lack a realistic clinical context and provide limited insight into how hallucinations can be mitigated in practice.

arXiv CS 8d ago

Measuring the sensitivity of LLM-based structured extraction to prompt, model, and schema choices in clinical discharge summaries

arXiv:2606.05970v1 Announce Type: new Abstract: Large language models are increasingly used for structured extraction from clinical free-text notes, but the sensitivity of their output to upstream configuration choices is less understood than their accuracy on fixed benchmarks. This work measures that sensitivity without human-annotated ground truth, by holding the extraction task fixed and varying one choice at a time. The fixed schema comprises 17 clinical documentation flags on a...

arXiv CS 5d ago

Routine laboratory trajectories encode the onset of organ-level complications in cancer

arXiv:2606.08538v1 Announce Type: new Abstract: Routine laboratory panels drawn during cancer treatment constitute longitudinal physiological recordings of organ function, yet their temporal structure is discarded by single-timepoint prognostic tools. A transformer trained on 2,777,595 laboratory measurements from 3,905 patients with multiple myeloma or ovarian cancer predicted the two-year onset of 162 treatment-associated complications, including therapy-related myelodysplastic syndromes,...

arXiv CS 1d ago